Last reviewed · How we verify
NCT07475897: NPWT-Pain Stud
Negative Pressure Wound Therapy as a Predictor of Persistent Pain After War-Related Trauma
trial in Phantom Limb Pain After Amputation in 150 participants. Not yet recruiting.
15 March 2026
Quick facts
| Lead sponsor | Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans) |
|---|---|
| Status | Not yet recruiting |
| Study type | OBSERVATIONAL |
| Enrollment | 150 |
| Start date | 15 March 2026 |
| Primary completion | 15 March 2026 |
| Estimated completion | 15 March 2026 |
| Sites | 1 location across Ukraine |
Conditions studied
- Phantom Limb Pain After Amputation — all drugs for Phantom Limb Pain After Amputation →
- Chronic Pain Due to Injury — all drugs for Chronic Pain Due to Injury →
- Postoperative Pain — all drugs for Postoperative Pain →
- Trauma (Including Fractures) — all drugs for Trauma (Including Fractures) →
Sponsor
Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans) — full company profile →
Who can join
Adults 18 to 60, any sex, with Phantom Limb Pain After Amputation or Chronic Pain Due to Injury. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
War-related trauma frequently causes complex soft tissue injuries that require repeated surgical treatment and advanced wound management techniques such as Negative Pressure Wound Therapy (NPWT). Although NPWT is widely used to promote wound healing and prepare wounds for reconstruction, its relationship with long-term pain outcomes remains unclear. This prospective cohort study aims to investigate whether the use of NPWT after war-related trauma is associated with an increased risk of persistent post-traumatic pain six months after injury. Adult patients with traumatic soft tissue injuries requiring surgical management will be enrolled and followed for six months. In addition to NPWT exposure, the study will evaluate several early clinical predictors of chronic pain, including acute pain intensity, number of surgical debridements, suspected nerve injury, and mechanism of trauma. Understanding these predictors may help clinicians identify high-risk patients early and develop targeted strategies for pain prevention and rehabilitation after severe trauma.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07475897
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Phantom Limb Pain After Amputation
Currently open trials in the same condition.
- NCT07324109 — Clinical Application Observation on the Evaluation of Phantom Limb Pain With the Suralis System · NA · recruiting
Other Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans) trials
Trials by the same sponsor.
- NCT07502313 — Evacuation Time and Tourniquet Use as Risk Factors for PTSD in Combat-Related Amputation · not yet recruiting
- NCT07475910 — Venous Thromboembolism and Chronic Pain After Major Limb Trauma · not yet recruiting
- NCT07475871 — Tourniquet Exposure and Risk of Chronic Pain After Severe Limb Trauma · not yet recruiting
- NCT07474506 — From Battlefield to Recovery: Continuous Regional Anaesthesia for War-Related Lower Limb Trauma · not yet recruiting
- NCT07432685 — Kinematics-Based Prediction of Chronic Pain After Combat-Related Extremity Trauma · enrolling by invitation
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07475897 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans)
- Last refreshed: 18 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07475897.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing