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NCT07467421
"Effectiveness of Physical Therapy Added to Transforaminal Injection in Lumbar Radicular Pain"
NA trial testing TFESE in Lumbar Disc Herniation With Radiculopathy in 76 participants. Completed in 31 December 2025.
31 December 2025
Quick facts
| Lead sponsor | Ankara Training and Research Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 76 |
| Start date | 1 June 2025 |
| Primary completion | 31 December 2025 |
| Estimated completion | 31 December 2025 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- TFESE
- TFESE+ CONVENTIONAL PHYSIOTHERAPY
Conditions studied
- Lumbar Disc Herniation With Radiculopathy — all drugs for Lumbar Disc Herniation With Radiculopathy →
- Low Back Pain (LBP) — all drugs for Low Back Pain (LBP) →
Sponsor
Ankara Training and Research Hospital
Who can join
Adults 18 to 65, any sex, with Lumbar Disc Herniation With Radiculopathy or Low Back Pain (LBP). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to investigate whether adding conventional physical therapy modalities to transforaminal epidural steroid injection (TFESE) provides additional benefits in patients with acute radicular pain due to lumbar disc herniation. While TFESE is a known effective treatment for radicular pain, this research aims to evaluate if physical therapy can further improve pain duration, functional level, disability, and depression scores. Participants will be divided into two groups based on their ability to attend a physical therapy program: Group 1: Patients receiving only ultrasound-guided TFESE and a standard home exercise program. Group 2: Patients receiving ultrasound-guided TFESE combined with 10 sessions of physical therapy (including hot-pack, therapeutic ultrasound, and TENS) and a standard home exercise program. The study will compare the effects of these treatments on pain intensity, disability, spinal range of motion, and depression levels. Assessments will be conducted at baseline (before injection), 1 hour after injection, and at the 1st and 3rd-month follow-up visits.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07467421
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Other Ankara Training and Research Hospital trials
Trials by the same sponsor.
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- NCT07161895 — Kinesiophobia and Its Impact on Pain and Function in Knee Osteoarthritis · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07467421 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ankara Training and Research Hospital
- Last refreshed: 31 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07467421.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing