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NCT06946030

Pseudoexfoliation and Carpal Tunnel Study

Completed Last updated 17 April 2026
What this trial tests

trial in Pseudoexfoliation Syndrome in 159 participants. Completed in 30 January 2026.

Timeline
1 May 2025
Primary endpoint
15 January 2026
30 January 2026

Quick facts

Lead sponsorAnkara Training and Research Hospital
StatusCompleted
Study typeOBSERVATIONAL
Enrollment159
Start date1 May 2025
Primary completion15 January 2026
Estimated completion30 January 2026
Sites1 location across Turkey (Türkiye)

Conditions studied

Sponsor

Ankara Training and Research Hospital

Who can join

Adults 50 to 80, any sex, with Pseudoexfoliation Syndrome or Carpal Tunnel Syndrome (CTS). Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This prospective, single-center case-control study aimed to investigate the association between pseudoexfoliation syndrome (PES) and carpal tunnel syndrome (CTS) using biochemical markers. A total of 159 participants aged 50-80 years were categorized into PES, CTS, and control groups. Diagnoses were confirmed by slit-lamp biomicroscopy for PES and electrophysiological evaluation (EMG) for CTS. Serum biomarkers, including homocysteine, methylmalonic acid, paraoxonase-1 (PON1), homocysteine thiolactonase (HTLase), and matrix metalloproteinases (MMP-2 and MMP-9), were measured. Group comparisons, diagnostic performance (ROC analysis), and independent associations (multinomial logistic regression) were evaluated. Comorbidities were recorded and analyzed in subgroup analyses.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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Other recruiting trials for Pseudoexfoliation Syndrome

Currently open trials in the same condition.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06946030.

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