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NCT07465237

Pressure Rise Time Modulation During Volume-Guaranteed Neonatal Ventilation

Completed NA Last updated 11 March 2026
What this trial tests

NA trial testing Pressure Rise Time Adjustment in Respiratory Distress in Neonates in 17 participants. Completed in 15 July 2024.

Timeline
15 July 2023
Primary endpoint
15 July 2024
15 July 2024

Quick facts

Lead sponsorHacettepe University
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposebasic science
Enrollment17
Start date15 July 2023
Primary completion15 July 2024
Estimated completion15 July 2024
Sites1 location across Turkey (Türkiye)

Drugs / interventions tested

Conditions studied

Sponsor

Hacettepe University

Who can join

Adults 0 Days to 28 Days, any sex, with Respiratory Distress in Neonates or Mechanical Ventilation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study investigates the short-term physiological effects of pressure rise time modulation during volume-guaranteed ventilation in neonates. Pressure rise time is an adjustable parameter that influences how quickly inspiratory pressure reaches the target level during mechanical ventilation. In this study, different pressure rise time settings will be applied during volume-guaranteed ventilation, and their effects on respiratory parameters, gas exchange, and patient-ventilator interaction will be evaluated. The aim is to determine whether modulation of pressure rise time has measurable short-term physiological effects in ventilated neonates and to identify optimal ventilator settings that may improve respiratory support.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Short-term physiological effects of pressure rise time modulation during volume-guaranteed neonatal ventilation.
    Aliyev F, Yigit S, Yucel E, Tandircioğlu UA. · · 2026 · PMID 41912661 · DOI 10.1038/s41598-026-44486-5

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Other Hacettepe University trials

Trials by the same sponsor.

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