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NCT07465237
Pressure Rise Time Modulation During Volume-Guaranteed Neonatal Ventilation
NA trial testing Pressure Rise Time Adjustment in Respiratory Distress in Neonates in 17 participants. Completed in 15 July 2024.
15 July 2024
Quick facts
| Lead sponsor | Hacettepe University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 17 |
| Start date | 15 July 2023 |
| Primary completion | 15 July 2024 |
| Estimated completion | 15 July 2024 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Pressure Rise Time Adjustment
Conditions studied
- Respiratory Distress in Neonates — all drugs for Respiratory Distress in Neonates →
- Mechanical Ventilation — all drugs for Mechanical Ventilation →
Sponsor
Hacettepe University
Who can join
Adults 0 Days to 28 Days, any sex, with Respiratory Distress in Neonates or Mechanical Ventilation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study investigates the short-term physiological effects of pressure rise time modulation during volume-guaranteed ventilation in neonates. Pressure rise time is an adjustable parameter that influences how quickly inspiratory pressure reaches the target level during mechanical ventilation. In this study, different pressure rise time settings will be applied during volume-guaranteed ventilation, and their effects on respiratory parameters, gas exchange, and patient-ventilator interaction will be evaluated. The aim is to determine whether modulation of pressure rise time has measurable short-term physiological effects in ventilated neonates and to identify optimal ventilator settings that may improve respiratory support.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Short-term physiological effects of pressure rise time modulation during volume-guaranteed neonatal ventilation.
Aliyev F, Yigit S, Yucel E, Tandircioğlu UA. · · 2026 · PMID 41912661 · DOI 10.1038/s41598-026-44486-5
Verify or expand the search:
- PubMed search for NCT07465237
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07465237 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Hacettepe University
- Last refreshed: 11 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07465237.
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