Last reviewed · How we verify
NCT07524842
Clinical Performance of Three Different Restorative Materials
NA trial testing bioactive composite in Tooth Disease in 60 participants. Not yet recruiting.
28 June 2026
Quick facts
| Lead sponsor | Hacettepe University |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 60 |
| Start date | 28 April 2026 |
| Primary completion | 28 June 2026 |
| Estimated completion | 28 June 2028 |
Drugs / interventions tested
- bioactive composite
- nanohybrid resin composite
- bulk-fill resin composite
Conditions studied
- Tooth Disease — all drugs for Tooth Disease →
Sponsor
Hacettepe University
Who can join
Adults 18 to 65, any sex, with Tooth Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The clinical performance of a bioactive composite (alkasite-based), a nanohybrid resin composite and a bulk-fill resin composite in class II restorations will be evaluated and compared. After recruiting participants with at least 3 approximal caries lesions, all restorations will be placed by a single clinician. All caries lesions will be removed before restoring. Cavities will be divided into three groups: a bioactive composite \[Cention Forte Ivoclar Vivadent, Schaan, Liechtenstein\], a nanohybrid resin composite \[Tetric N-Ceram2 (Ivoclar Vivadent, Schaan, Liechtenstein)\] and a bulk-fill resin composite \[Tetric N-PowerFill2 (Ivoclar Vivadent, Schaan, Liechtenstein)\], All restorative procedures will be conducted according to manufacturers' instructions. Restorations will be scored using FDI criteria after a week (baseline) 6, 12, 24, 36 and 48 months. Descriptive statistics will be performed using chi-square tests.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07524842
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of bioactive composite
Trials testing the same drug.
- NCT07432724 — This Study is Conducted to Evaluate the 18-month Clinical Performance of Complete Bioactive Restorative System for Occlu · NA · not yet recruiting
- NCT04825379 — Clinical Evaluation of a Bioactive Material · NA · active not recruiting
Other recruiting trials for Tooth Disease
Currently open trials in the same condition.
- NCT06778590 — Comparison of Piezoelectric and Conventional Surgery for Germectomy of the Lower Third Molar · NA · recruiting
- NCT04825379 — Clinical Evaluation of a Bioactive Material · NA · active not recruiting
- NCT04685967 — Clinical Evaluation of a Restorative Glass Ionomer and a Bulk-fill Composite Resin · NA · active not recruiting
Other Hacettepe University trials
Trials by the same sponsor.
- NCT07522060 — Early Functional Response as a Predictor of Clinical Outcomes in Hand Rehabilitation: A Prospective Feasibility Study Us · not yet recruiting
- NCT07390162 — The Effect of Changes in the Frequency of Endotracheal Tube Repositioning in Intensive Care Units on the Prevention of O · NA · not yet recruiting
- NCT07579676 — DEVELOPMENT AND PSYCHOMETRIC EVALUATION OF THE NEUROCOGNITIVE UPPER EXTREMITY TESTS: A RELIABILITY AND VALIDITY STUDY · not yet recruiting
- NCT07439861 — The Effect of Cognitive Dual-Task on Athletic Performance Parameters in Volleyball Players With and Without Chronic Ankl · not yet recruiting
- NCT07459361 — Acute Effects of Wearable Electrical Stimulation in Stroke · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07524842 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Hacettepe University
- Last refreshed: 13 April 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07524842.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing