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NCT07447063: iDOSE
The Impact of Dietary Salt on the Severity of Eczema
Phase 4 trial testing Sodium chloride tablets in Eczema in 40 participants. Not yet recruiting.
5 March 2028
Quick facts
| Lead sponsor | University of California, San Francisco |
|---|---|
| Phase | Phase 4 |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | triple |
| Primary purpose | prevention |
| Enrollment | 40 |
| Start date | 6 March 2026 |
| Primary completion | 5 March 2028 |
| Estimated completion | 5 May 2028 |
| Sites | 2 locations across United States |
Drugs / interventions tested
- Sodium chloride tablets
- Placebo Tablets — full drug profile →
Conditions studied
- Eczema — all drugs for Eczema →
- Atopic Dermatitis — all drugs for Atopic Dermatitis →
Sponsor
University of California, San Francisco
Who can join
18 and older, any sex, with Eczema or Atopic Dermatitis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this clinical trial is to evaluate the feasibility of low-sodium diet to improve eczema severity. The main questions it aims to answer are: * Does a low-sodium diet improve eczema severity? * How does a low-sodium diet impact skin sodium concentration? * Is skin sodium concentration associated with eczema severity? Researchers will ask all participant to follow a low-sodium diet, then compare sodium tablets to a placebo (a look-alike substance that contains no drug) to specifically examine the impact of altering sodium intake. Participants will: * Follow a low-salt diet for the duration of the 24-week study * Take sodium chloride tablets every day for 5 weeks followed by a placebo every day for 5 weeks after a 2-week washout period, or vice versa * Complete up to 4 virtual check-in visits * Visit the clinic 4 times to answer questionnaires, provide bio samples, complete dietary recalls, and undergo non-contrast sodium MRI
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07447063
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Sodium chloride tablets
Trials testing the same drug.
- NCT07487831 — The Impact of Salt Intake on Sodium in the Skin and Inflammatory Skin Disease · Phase 4 · not yet recruiting
Other recruiting trials for Eczema
Currently open trials in the same condition.
- NCT07463079 — Clinical Evaluation of a Soothing Moisturizing Lotion in Individuals With Atopic Eczema · NA · recruiting
- NCT06807268 — A Study of the Medicine Called Abrocitinib in Children 6 to Less Than 12 Years of Age With Moderate-to-Severe Eczema · Phase 3 · recruiting
- NCT07355075 — A Study to Assess the Efficacy of GX-03 in Moderate to Severe Eczema (Atopic Dermatitis) · Phase 2 · recruiting
- NCT06998446 — Sodium in the Skin and Atopic Dermatitis · recruiting
- NCT06994520 — Efficacy of Topical Cannabidiol for Eczema · Phase 2 · active not recruiting
Other University of California, San Francisco trials
Trials by the same sponsor.
- NCT05284773 — Screening for Acute Malnutrition · NA · withdrawn
- NCT04634851 — Video Home Visits for Dietary Counselling · NA · not yet recruiting
- NCT06065670 — Assessing Changes in Multi-parametric MRI in Patients With Acute Demyelinating Lesions Taking Clemastine Fumarate as a M · Phase 1, PHASE2 · not yet recruiting
- NCT07534098 — Intervention for Hearing Health Among Native Americans · NA · not yet recruiting
- NCT06960421 — Exercise-based Frailty Intervention in Lung Transplantation (XFIT) · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07447063 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of California, San Francisco
- Last refreshed: 17 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07447063.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing