NCT07445321 (Premolar) is a NA clinical trial of Space Closure in Orthodontic Extraction, sponsored by Dow University of Health Sciences.

Who is sponsoring NCT07445321?

NCT07445321 is sponsored by Dow University of Health Sciences.

What drugs are being tested in NCT07445321?

Interventions in NCT07445321: Space Closure.

What condition does NCT07445321 study?

NCT07445321 studies Orthodontic Extraction.

Is NCT07445321 still recruiting?

NCT07445321 is currently completed. Last updated 3 March 2026.

Last reviewed 2026-03-03 · How we verify

NCT07445321: Premolar

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Comparison of Rate and Amount of Orthodontic Space Closure

Completed NA Last updated 3 March 2026

What this trial tests

NA trial testing Space Closure in Orthodontic Extraction in 34 participants. Completed in 9 February 2024.

Timeline

15 February 2023

Primary endpoint
20 December 2023

9 February 2024

Quick facts

Lead sponsor	Dow University of Health Sciences
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	34
Start date	15 February 2023
Primary completion	20 December 2023
Estimated completion	9 February 2024
Sites	1 location across Pakistan

Drugs / interventions tested

Space Closure

Conditions studied

Orthodontic Extraction — all drugs for Orthodontic Extraction →

Sponsor

Dow University of Health Sciences

Who can join

Adults 18 to 35, any sex, with Orthodontic Extraction. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this clinical trial is to compare rate and amount of space closure among fresh vs healed extraction sites during fixed orthodontic treatment in patients with all first premolar's extraction Primary outcome measure is to calculate rate and amount of space closure between fresh vs healed as well as maxilla and mandible.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other Dow University of Health Sciences trials

Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT07445321 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Dow University of Health Sciences
Last refreshed: 3 March 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07445321.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing