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NCT07526818
Comparison of Manual and Mechanical Glide Path Techniques for Measuring Root Canal Length Using Standalone Apex Locator and an Endomotor With built-in Apex Locator.
NA trial testing Endomotor with built-in apex locator E Connect S+ in Endodontic Treatment in 104 participants. Participants enrolled and being followed up; not accepting new ones.
25 March 2027
Quick facts
| Lead sponsor | Dow University of Health Sciences |
|---|---|
| Phase | NA |
| Status | Active, enrolled |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | other |
| Enrollment | 104 |
| Start date | 26 March 2026 |
| Primary completion | 25 March 2027 |
| Estimated completion | 25 March 2027 |
| Sites | 1 location across Pakistan |
Drugs / interventions tested
- Endomotor with built-in apex locator E Connect S+
- Electronic Apex locators
Conditions studied
- Endodontic Treatment — all drugs for Endodontic Treatment →
Sponsor
Dow University of Health Sciences
Who can join
Adults 18 to 60, any sex, with Endodontic Treatment. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study is designed to compare two commonly used methods for measuring the length of the root canal during root canal treatment. Accurate measurement of the root canal is very important because it helps dentists clean, shape, and fill the canal properly, which improves the success of the treatment and reduces the risk of complications. In this study, two different techniques will be evaluated. The first method uses small hand instruments (manual technique) to create a smooth pathway inside the root canal before measuring its length. The second method uses a machine-assisted system (mechanical technique) that creates this pathway automatically. Both methods use special electronic devices called apex locators, which help determine the exact length of the root canal more accurately than traditional X-rays alone. Participants in this study will be patients who require root canal treatment on lower molar teeth. If you agree to take part, you will receive standard root canal treatment similar to routine dental care. The only difference is the method used to prepare the canal and measure its length, which will be randomly assigned. This means neither you nor the dentist will choose the method, ensuring fair comparison. The procedure will include taking dental X-rays, administering local anesthesia, cleaning and shaping the root canal, and filling it after measurement. All steps follow standard dental practices and safety protocols. Your treatment will not be compromised in any way by participating in the study. The purpose of this research is to determine which method is more accurate, efficient, and reliable. The results may help improve future dental treatments by guiding dentists toward better techniques, ultimately benefiting patients through safer and more effective care. Participation in this study is completely voluntary. You have the right to refuse participation or withdraw at any time without affecting your dental treatment. All personal and medical information will be kept confidential and used only for research purposes. There are minimal risks involved, as all procedures are part of routine root canal treatment. You may not receive direct personal benefit, but your participation will contribute to improving dental care for others in the future.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07526818
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07526818 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Dow University of Health Sciences
- Last refreshed: 13 April 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07526818.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing