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NCT07435727
Comparison of Speaking Valve Trial and Capping Trial for Tracheostomy Decannulation in Stroke Patients
NA trial testing Passy-Muir Speaking Valve in Stroke in 120 participants. Not yet recruiting.
1 April 2027
Quick facts
| Lead sponsor | Hongying Jiang, MD |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 120 |
| Start date | 1 April 2026 |
| Primary completion | 1 April 2027 |
| Estimated completion | 1 July 2027 |
| Sites | 1 location across China |
Drugs / interventions tested
- Passy-Muir Speaking Valve
- Tracheostomy tube capping
Conditions studied
- Stroke — all drugs for Stroke →
Sponsor
Hongying Jiang, MD
Who can join
Adults 18 to 80, any sex, with Stroke. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study aims to compare the efficacy and safety of the Speaking Valve trial versus the traditional Capping trial as indicators for tracheostomy decannulation in stroke patients. The trial is a prospective, multicenter, randomized, parallel-group, outcomes-assessor-blinded study with an exploratory crossover design.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07435727
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Passy-Muir Speaking Valve
Trials testing the same drug.
- NCT07005596 — Early Speaking Valve in Ventilator Weaning: Effects on Communication, Depression, and Quality of Life · NA · not yet recruiting
Other recruiting trials for Stroke
Currently open trials in the same condition.
- NCT06615973 — Screening for Social Determinants of Health (SDOH) and Cognitive Function in Individuals With History of Stroke · recruiting
- NCT07494890 — Measurement Properties of Mechanical Cost of Walking for Individuals With Walking Impairment · NA · recruiting
- NCT07356011 — Exoskeleton for Balance · NA · recruiting
- NCT07523503 — Unilateral Versus Bilateral Task-specific Training on Motor Impairment, Upper Extremity Function, and Hand Dexterity in · NA · recruiting
- NCT06704074 — Virtual Reality Task Oriented Training on Upper Limb Function in Stroke Patients · NA · recruiting
Other Hongying Jiang, MD trials
Trials by the same sponsor.
- NCT07521540 — Integrated Rehabilitation in HDU for Post-Intensive Care SyndromeLiberation in Patients With PICS · NA · not yet recruiting
- NCT07183670 — Standardized Tracheostomy Decannulation Protocol for Patients With Prolonged Disorders of Consciousness · enrolling by invitation
- NCT07173634 — Speaking Valve Trial vs. Capping Trial for Tracheostomy Decannulation in Prolonged Disorders of Consciousness · NA · enrolling by invitation
- NCT07317791 — Cough Flow as a Criterion Decannulation Threshold in Prolonged Tracheostomy Patients · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07435727 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Hongying Jiang, MD
- Last refreshed: 27 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07435727.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing