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NCT07183670: STEP-DoC
Standardized Tracheostomy Decannulation Protocol for Patients With Prolonged Disorders of Consciousness
trial testing decannulation protocol in Prolonged Disorders of Consciousness in 300 participants. Enrolling by invitation.
1 February 2027
Quick facts
| Lead sponsor | Hongying Jiang, MD |
|---|---|
| Status | ENROLLING BY INVITATION |
| Study type | OBSERVATIONAL |
| Enrollment | 300 |
| Start date | 1 February 2026 |
| Primary completion | 1 February 2027 |
| Estimated completion | 1 May 2027 |
| Sites | 2 locations across China |
Drugs / interventions tested
- decannulation protocol
Conditions studied
- Prolonged Disorders of Consciousness — all drugs for Prolonged Disorders of Consciousness →
- Tracheostomy — all drugs for Tracheostomy →
Sponsor
Hongying Jiang, MD
Who can join
Adults 18 to 80, any sex, with Prolonged Disorders of Consciousness or Tracheostomy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
To evaluate the feasibility of a standardized tracheostomy decannulation protocol for patients with prolonged Disorders of Consciousness (pDoC) in rehabilitation hospitals.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07183670
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Prolonged Disorders of Consciousness
Currently open trials in the same condition.
- NCT06473285 — Effects of Esketamine on Consciousness-related Brain Network Characteristics in Patients With Prolonged Disorders of Con · NA · recruiting
Other Hongying Jiang, MD trials
Trials by the same sponsor.
- NCT07521540 — Integrated Rehabilitation in HDU for Post-Intensive Care SyndromeLiberation in Patients With PICS · NA · not yet recruiting
- NCT07435727 — Comparison of Speaking Valve Trial and Capping Trial for Tracheostomy Decannulation in Stroke Patients · NA · not yet recruiting
- NCT07173634 — Speaking Valve Trial vs. Capping Trial for Tracheostomy Decannulation in Prolonged Disorders of Consciousness · NA · enrolling by invitation
- NCT07317791 — Cough Flow as a Criterion Decannulation Threshold in Prolonged Tracheostomy Patients · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07183670 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Hongying Jiang, MD
- Last refreshed: 24 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07183670.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing