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NCT07432945
In Vivo Exposure vs. Videochat-Based Vicarious Exposure
NA trial testing In Vivo Exposure Training (IVET) in Anxiety in 72 participants. Currently enrolling.
31 December 2026
Quick facts
| Lead sponsor | Ruhr University of Bochum |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 72 |
| Start date | 26 February 2026 |
| Primary completion | 31 December 2026 |
| Estimated completion | 31 December 2026 |
| Sites | 1 location across Germany |
Drugs / interventions tested
- In Vivo Exposure Training (IVET)
- Vicarious Exposure Training (VicET)
Conditions studied
- Anxiety — all drugs for Anxiety →
- Anxiety Disorders — all drugs for Anxiety Disorders →
Sponsor
Ruhr University of Bochum
Who can join
Adults 18 to 65, any sex, with Anxiety or Anxiety Disorders. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
After screening (including parts of the Mini-DIPS), participants will receive a pre-assessment with a baseline heartrate measurement, self-report measures and two BATs (with the treated spider and the non-treated spider). All participants receive a brief psychoeducation \& video demonstration of exposure steps. Participants are randomly assigned to the three study arms and are then set to receive a single session of either in vivo exposure (IVET), videochat based vicarious exposure (VicET) or neither (Waiting List Control, WLC). Approximately 24 hours later, the two BATs with both spiders, a slightly reduced set of self-report measures and an interview will conduct the post-assessment. The order of all BATs, the spider individuals (treated vs. non-treated spider) and assignment to study arms will be randomized using a list that will be worked through in a sequence determined using "www.random.org". At a six-week follow-up, another long-term assessment will be conducted. Here, participants will receive a brief online questionnaire related to their experiences with spiders and self-report measures that were previously administered. Participants previously assigned to the waiting list control (WLC) will be invited to participate in an in-vivo exposure session. A set of questionnaires including demographic information, VAS scales on the current psychological state and wellbeing (administered at the start and end of the first and second assessment day), the BDI-II, the STAI-T and STAI-S, FEE, SPQ, SBQ, FSQ, GSE, SEQ-SP, TC/E for treatment credibility and the "positive attitudes towards technology subscale" of the MTUA will be used. BDI-II, STAI and MTUA are only administered at pre-assessment. The SAS is used for initial screening.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07432945
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Ruhr University of Bochum trials
Trials by the same sponsor.
- NCT06255821 — The Effect of Time on Generalization of Exposure-based Benefit · NA · completed
- NCT05824884 — Self-efficacy Enhancement in a Virtual Reality Training for Fear of Heights · NA · recruiting
- NCT05798078 — The Relationship Between Social Anxiety and Anxious Thinking Styles · NA · completed
- NCT05780203 — CBM in the Context of Exposure for Acrophobia · NA · completed
- NCT05718271 — Effects of Verbal Instructions on Fear Extinction and Extinction Retrieval · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07432945 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ruhr University of Bochum
- Last refreshed: 2 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07432945.
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