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NCT07425249
Impact of Chewing Gum on Postoperative Gut Motility in Gastrointestinal Surgery Patients
NA trial testing Chewing Gum in Postoperative Ileus in 96 participants. Currently enrolling.
25 August 2026
Quick facts
| Lead sponsor | Khyber Medical University Peshawar |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 96 |
| Start date | 1 January 2026 |
| Primary completion | 25 August 2026 |
| Estimated completion | 29 October 2026 |
| Sites | 1 location across Pakistan |
Drugs / interventions tested
- Chewing Gum — full drug profile →
Conditions studied
- Postoperative Ileus — all drugs for Postoperative Ileus →
- Delayed Gastrointestinal Motility — all drugs for Delayed Gastrointestinal Motility →
- Postoperative Gut Dysfunction — all drugs for Postoperative Gut Dysfunction →
Sponsor
Khyber Medical University Peshawar
Who can join
Adults 17 to 85, any sex, with Postoperative Ileus or Delayed Gastrointestinal Motility. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Postoperative ileus (POI) is a frequent complication after abdominal surgery, leading to delayed gastrointestinal motility, prolonged hospital stay, and increased patient discomfort. Chewing gum, as a form of sham feeding, has been proposed to stimulate gut motility through vagal stimulation and increased gastrointestinal secretions. This randomized controlled trial aims to assess the effect of chewing gum on early recovery of gastrointestinal motility in patients undergoing open gastrointestinal surgery.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07425249
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Chewing Gum
Trials testing the same drug.
- NCT07517926 — Chewing Gum and Cold Gargle on Post-Bronchoscopy Symptoms · NA · recruiting
- NCT07053956 — Impact of Chewing Gum on FeNO Levels in Patients With Bronchial Asthma · NA · completed
- NCT06192394 — Effect of Gum Chewing or Walking on Bowel Prep Quality and Patient Satisfaction Before Colonoscopy · NA · completed
- NCT06168981 — The Effect of Preoperative Chewing Gum on Anxiety and Sore Throat in Patients With Laryngeal Mask Airway · NA · unknown
- NCT04191694 — Chewing Gum to Prevent Nausea and Vomiting After Caesarean Section Under Spinal Anaesthesia · NA · unknown
Other recruiting trials for Postoperative Ileus
Currently open trials in the same condition.
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- NCT06974500 — Implementation of an Efferent Loop Stimulation Protocol Prior to Ileostomy Closure at La Paz University Hospital · recruiting
- NCT07014046 — Simple Bed Exercises for Reducing Postoperative Ileus in Colorectal Surgical Patients. · NA · recruiting
- NCT05344417 — Low Pressure Pneumoperitoneum and Postoperative Ileus · NA · recruiting
Other Khyber Medical University Peshawar trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07425249 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Khyber Medical University Peshawar
- Last refreshed: 20 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07425249.
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