Last reviewed · How we verify
NCT06974500
Implementation of an Efferent Loop Stimulation Protocol Prior to Ileostomy Closure at La Paz University Hospital
trial testing Daily efferent limb stimulation for at least two weeks prior to surgery using saline solution and a thickering agent in Postoperative Ileus in 68 participants. Currently enrolling.
1 January 2027
Quick facts
| Lead sponsor | Hospital Universitario La Paz |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 68 |
| Start date | 1 January 2025 |
| Primary completion | 1 January 2027 |
| Estimated completion | 1 April 2027 |
| Sites | 1 location across Spain |
Drugs / interventions tested
- Daily efferent limb stimulation for at least two weeks prior to surgery using saline solution and a thickering agent
Conditions studied
- Postoperative Ileus — all drugs for Postoperative Ileus →
- Colorectal Cancer Control and Prevention — all drugs for Colorectal Cancer Control and Prevention →
- Stoma - Ileostomy — all drugs for Stoma - Ileostomy →
Sponsor
Hospital Universitario La Paz
Who can join
18 and older, any sex, with Postoperative Ileus or Colorectal Cancer Control and Prevention. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Stoma creation is a common surgical procedure, employed in certain contexts within general surgery, particularly in colorectal and emergency surgery. Although stoma formation is a life-saving technique, the diversion of intestinal contents has pathophysiological, aesthetic, and psychological repercussions on patients' lives. Stomas may be either permanent or temporary. In temporary cases, a second intervention is required to perform ileostomy closure and restore normal intestinal transit. Several studies indicate that stimulation of the efferent loop prior to ileostomy closure yields benefits in patients' postoperative outcomes. Currently, there is no established protocol for this intervention at Hospital Universitario La Paz. However, implementing such a protocol-given that it is a simple, inexpensive, and accessible intervention-could offer significant cost-effectiveness. It may reduce complications and hospital stay, improve patients' quality of life, and represent a valuable contribution to the General Surgery Departmen
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06974500
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Postoperative Ileus
Currently open trials in the same condition.
- NCT07440667 — Restrictive vs Liberal Intraoperative Fluid Strategy and Postoperative Outcomes After Elective Cesarean Section · NA · recruiting
- NCT07425249 — Impact of Chewing Gum on Postoperative Gut Motility in Gastrointestinal Surgery Patients · NA · recruiting
- NCT07071987 — Effect of Thread Embedding Acupuncture on Postoperative Ileus Recovery After Colorectal Cancer Surgery: A Multicenter Ra · NA · recruiting
- NCT07014046 — Simple Bed Exercises for Reducing Postoperative Ileus in Colorectal Surgical Patients. · NA · recruiting
- NCT05344417 — Low Pressure Pneumoperitoneum and Postoperative Ileus · NA · recruiting
Other Hospital Universitario La Paz trials
Trials by the same sponsor.
- NCT07479927 — Telematic Cognitive Training and Mindfulness in Pediatric Patients After CAR-T Cell Therapy, Single Hematopoietic Alloge · NA · recruiting
- NCT07260643 — SiLaC Laser Technique for Pilonidal Sinus - La Paz Cohort Study. · not yet recruiting
- NCT07203664 — Use of Tacrolimus and MTOR Inhibitors With Anticipatory Therapy vs. Tacrolimus and Mycophenolic Acid With Universal Prop · Phase 4 · not yet recruiting
- NCT07023601 — International Prospective Multicentre Study That Evaluate the Sentinel Lymph Node Detection Rate in Patients With First · NA · enrolling by invitation
- NCT03086850 — Long-term Effect of the Physical Activity Promotion on the Clinical Characteristics and Vascular Risk in Patients With M · NA · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06974500 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Hospital Universitario La Paz
- Last refreshed: 16 May 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06974500.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing