Last reviewed · How we verify
NCT07424170
The Effect of Exercise-Induced Irisin on Brain Function and Postoperative Delirium in Older Adults
trial testing Preoperative physical activity level in Post Operative Delirium in 140 participants. Not yet recruiting.
26 December 2026
Quick facts
| Lead sponsor | Peking University People's Hospital |
|---|---|
| Status | Not yet recruiting |
| Study type | OBSERVATIONAL |
| Enrollment | 140 |
| Start date | 15 March 2026 |
| Primary completion | 26 December 2026 |
| Estimated completion | 31 December 2026 |
Drugs / interventions tested
- Preoperative physical activity level
Conditions studied
- Post Operative Delirium — all drugs for Post Operative Delirium →
Sponsor
Peking University People's Hospital
Who can join
65 and older, any sex, with Post Operative Delirium. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this observational study is to learn how exercise-induced irisin protects the brain. It also explores irisin's effect on postoperative delirium (POD) in older adults. The main questions it aims to answer are: Does daily activity link to POD? Does irisin play a mediating role in this process? Researchers will enroll active and inactive adults aged 65 and older. All will have surgery under spinal anesthesia. The researchers will measure irisin levels in spinal fluid. They will track POD and other complications for five days after surgery.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07424170
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Post Operative Delirium
Currently open trials in the same condition.
- NCT06613178 — Intravenous Acetaminophen After Cardiac Surgery - Definitive Study · Phase 4 · recruiting
- NCT06355570 — Delirium After Cardiac Surgery in Intensive Care Units · NA · recruiting
- NCT05242419 — A Study of Huperzine A Injection in Reducing Postoperative Delirium in Elderly Patients Undergoing Non-cardiac Surgery · NA · recruiting
- NCT05765162 — Safe Brain Initiative, Operationalizing Precision Anaesthesia · recruiting
Other Peking University People's Hospital trials
Trials by the same sponsor.
- NCT07535645 — Baricitinib for Post-HSCT Persistent Thrombocytopenia · Phase 1, PHASE2 · not yet recruiting
- NCT07516002 — Immunoglobulin Efficacy and Immune Profiling in Antibody Immunodeficiency · not yet recruiting
- NCT07294339 — A Randomized Controlled Trial of Acupuncture for the Management of Hot Flashes in Patients With Hormone Receptor-Positiv · NA · not yet recruiting
- NCT07500441 — Digital PCR of CHIP and MR for MRD Monitoring After Allo-HSCT in AML · recruiting
- NCT07487883 — Cadherin 3(CDH3)-Targeted PET in Lung Malignant Tumors · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07424170 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Peking University People's Hospital
- Last refreshed: 10 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07424170.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing