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NCT07420608
Targeted Ankle Proprioceptive Training Improves Balance, Gait, and Functional Mobility in Chronic Stroke Survivors
NA trial testing Gait training in Proprioceptive Disorders in 140 participants. Completed in 31 December 2025.
31 December 2024
Quick facts
| Lead sponsor | Iqra National University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 140 |
| Start date | 1 January 2023 |
| Primary completion | 31 December 2024 |
| Estimated completion | 31 December 2025 |
| Sites | 1 location across Pakistan |
Drugs / interventions tested
- Gait training
Conditions studied
- Proprioceptive Disorders — all drugs for Proprioceptive Disorders →
- Balance; Distorted — all drugs for Balance; Distorted →
- Stroke Sequelae — all drugs for Stroke Sequelae →
Sponsor
Iqra National University
Who can join
18 and older, any sex, with Proprioceptive Disorders or Balance; Distorted. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Stroke is a leading cause of long-term disability, with balance and gait deficits affecting \>80% of survivors and increasing fall risk. Emerging evidence links ankle proprioceptive impairment-particularly inversion/eversion acuity-to these deficits, often bilateral and central in origin. Cross-sectional studies show strong associations, but causality, temporal progression, and intervention efficacy (especially in severe/non-ambulatory cases) remain unproven. This trial tests a targeted proprioceptive protocol against standard care.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Targeted ankle proprioceptive training improves balance, gait, and functional mobility in chronic stroke survivors: a multicenter randomized controlled trial with longitudinal follow-up.
Khan M, Alhammad AA, Alghadier M, Alnasser SM, et al · · 2026 · PMID 42216149 · DOI 10.1186/s12984-026-02031-5
Verify or expand the search:
- PubMed search for NCT07420608
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Gait training
Trials testing the same drug.
- NCT07093229 — Knee Osteoarthritis in Elderly People - Gait Analysis · NA · enrolling by invitation
- NCT05915130 — An Innovative Gait Training Program in Immersive Virtual Reality for Healthy Older Adults · NA · unknown
- NCT04292717 — Deficit-specific Training in Spinal Disorders · NA · completed
- NCT04650802 — Improving Propulsion of the Paretic Leg In Chronic Stroke · NA · completed
- NCT03522389 — Effect of Action Observation Training on Gait Variables and Global Cognitive Functions · NA · completed
Other recruiting trials for Proprioceptive Disorders
Currently open trials in the same condition.
- NCT03298243 — Use of Sensory Substitution to Improve Arm Control After Stroke · NA · recruiting
- NCT03881930 — Balance Rehabilitation With Modified Visual Input in Patients With Neuropathy · NA · recruiting
Other Iqra National University trials
Trials by the same sponsor.
- NCT07420569 — Multimodal Pelvic Floor Rehabilitation in Chronic Stroke Survivors: Long-Term Efficacy, Optimal Protocols, and Adjunctiv · NA · completed
- NCT07420595 — Gait Training for Concurrent Optimization of Weight Mgt,bp Regulation and Functional Mobility · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07420608 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Iqra National University
- Last refreshed: 19 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07420608.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing