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NCT07401446
Complication Rate of Onlay vs Sublay Mesh Repair in Incisional Hernia
NA trial testing Sublay Mesh Repair in Hernia in 350 participants. Completed in 15 September 2025.
31 August 2025
Quick facts
| Lead sponsor | Hayat Abad Medical Complex, Peshawar |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 350 |
| Start date | 1 August 2020 |
| Primary completion | 31 August 2025 |
| Estimated completion | 15 September 2025 |
| Sites | 1 location across Pakistan |
Drugs / interventions tested
- Sublay Mesh Repair
- Onlay Mesh Repair
Conditions studied
- Hernia — all drugs for Hernia →
- Ventral Hernia Repair — all drugs for Ventral Hernia Repair →
- Incisional Hernia Repair — all drugs for Incisional Hernia Repair →
- Abdominal Wall Hernia — all drugs for Abdominal Wall Hernia →
Sponsor
Hayat Abad Medical Complex, Peshawar — full company profile →
Who can join
Adults 18 to 60, any sex, with Hernia or Ventral Hernia Repair. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This randomized controlled trial was conducted at the Department of Surgery, Hayatabad Medical Complex, Peshawar. Eligible patients with incisional hernia were randomized into two parallel groups: sublay mesh repair and onlay mesh repair. Procedures were performed by a single experienced general surgeon. Postoperative complications were assessed by an independent surgeon blinded to the type of procedure. Patients were followed for a period of three months to evaluate safety and recurrence outcomes.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07401446
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Sublay Mesh Repair
Trials testing the same drug.
- NCT07367321 — Comparison of Onlay Mesh Repair and Sublay Mesh Repair in Umbilical Hernia Surgery · NA · not yet recruiting
- NCT07140471 — Comparison of Sublay and Onlay Mesh Repair in Ventral Hernia · NA · completed
Other recruiting trials for Hernia
Currently open trials in the same condition.
- NCT07220382 — Preoperative BOTOX® Injection for Large Ventral Hernia Repair · Phase 4 · recruiting
- NCT07316426 — Preoptimisation in Ventral Hernia Surgery · NA · recruiting
- NCT07166172 — Prospective Registry for Long-term Outcomes Following FETO in Severe Left and Right CDH · NA · recruiting
- NCT06449378 — Transorb™ Self-Gripping Resorbable Mesh in High-risk Subjects Undergoing Open Repair of Ventral Hernia · NA · active not recruiting
- NCT06042205 — TISSIUM™ Atraumatic Hernia Repair System (TAHRS) Pilot Study · NA · active not recruiting
Other Hayat Abad Medical Complex, Peshawar trials
Trials by the same sponsor.
- NCT07055529 — Comparison of Efficacy and Safety Psoralen Combined With Ultraviolet A (PUVA) Vs Tofacitinib in the Treatment of General · EARLY_PHASE1 · not yet recruiting
- NCT07453238 — Comparison of Topical Calcipotriol and Intralesional Steroids in Alopecia Areata · Phase 4 · not yet recruiting
- NCT07437534 — Comparative Evaluation of the Safety and Effectiveness of Crisaborole Ointment (2%) Versus Tacrolimus Ointment (0.1%) fo · Phase 4 · not yet recruiting
- NCT07406204 — Tofacitinib vs Methotrexate for Severe Alopecia Areata (TOFA-MTX-AA) · Phase 4 · not yet recruiting
- NCT07441005 — Comparative Efficacy of Topical Oxiconazole Cream (1%) Versus Topical Clotrimazole Cream (1%) in the Treatment of Tinea · EARLY_PHASE1 · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07401446 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Hayat Abad Medical Complex, Peshawar
- Last refreshed: 10 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07401446.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing