NCT07316426 (PreOpt) is a NA clinical trial of preoptimisation programme in Hernia, sponsored by Umeå University.

Who is sponsoring NCT07316426?

NCT07316426 is sponsored by Umeå University.

What drugs are being tested in NCT07316426?

Interventions in NCT07316426: preoptimisation programme.

What condition does NCT07316426 study?

NCT07316426 studies Hernia, Hernia, Ventral, Hernia Incisional, Hernia, Umbilical.

Is NCT07316426 still recruiting?

NCT07316426 is currently recruiting now. Last updated 5 January 2026.

Last reviewed 2026-01-05 · How we verify

NCT07316426: PreOpt

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Preoptimisation in Ventral Hernia Surgery

Recruiting now NA Last updated 5 January 2026

What this trial tests

NA trial testing preoptimisation programme in Hernia in 130 participants. Currently enrolling.

Timeline

22 September 2025

Primary endpoint
1 September 2027

1 September 2029

Quick facts

Lead sponsor	Umeå University
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	prevention
Enrollment	130
Start date	22 September 2025
Primary completion	1 September 2027
Estimated completion	1 September 2029
Sites	5 locations across Sweden

Drugs / interventions tested

preoptimisation programme

Conditions studied

Hernia — all drugs for Hernia →
Hernia, Ventral — all drugs for Hernia, Ventral →
Hernia Incisional — all drugs for Hernia Incisional →
Hernia, Umbilical — all drugs for Hernia, Umbilical →

Sponsor

Umeå University

Who can join

18 and older, any sex, with Hernia or Hernia, Ventral. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The study is a multicentre, single-blinded, randomised controlled trial. Ventral hernia patients with an aperture width between four and eight centimetres are randomised to either participation in a multimodal preoptimisation programme, including interventions to increase physical activity, promote weight loss, and optimise the treatment of comorbidities, or to surgery without structured preoptimisation. The primary endpoint is complications at three months postoperatively. During surgery, biopsies of skin, muscle, and fascia will be collected, along with pre- and postoperative blood samples, to analyse the molecular effects of preoptimisation, particularly in relation to collagen metabolism.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other recruiting trials for Hernia

Currently open trials in the same condition.

NCT07220382 — Preoperative BOTOX® Injection for Large Ventral Hernia Repair · Phase 4 · recruiting
NCT07166172 — Prospective Registry for Long-term Outcomes Following FETO in Severe Left and Right CDH · NA · recruiting
NCT06449378 — Transorb™ Self-Gripping Resorbable Mesh in High-risk Subjects Undergoing Open Repair of Ventral Hernia · NA · active not recruiting
NCT06042205 — TISSIUM™ Atraumatic Hernia Repair System (TAHRS) Pilot Study · NA · active not recruiting
NCT03972956 — Samples Procurement for Colorectal Cancer, Gastric Cancer, and Non-malignant Disease · recruiting

Other Umeå University trials

Trials by the same sponsor.

NCT07407946 — Blended Trauma-Focused Cognitive Behavioral Therapy With Compassion · NA · recruiting
NCT07346820 — VDJ-recombination of the B-cell Receptor Following Hematopoietic Stem Cell Transplantation · not yet recruiting
NCT07417358 — Single-Stapled Technique for Colorectal Anastomosis · recruiting
NCT07170722 — Sub-threshold DRG Stimulation vs Sham in Established Responders · NA · completed
NCT07038811 — Implementation of the App Tät®II for Treatment of Urgency and Mixed Urinary Incontinence · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT07316426 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Umeå University
Last refreshed: 5 January 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07316426.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing