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NCT07391202
Crown Removal in Non-Surgical Peri-Implantitis Therapy: A Randomized Trial
NA trial testing Non-Surgical Peri-Implant Therapy without Crown in Peri-implantitis in 36 participants. Not yet recruiting.
31 July 2027
Quick facts
| Lead sponsor | G. d'Annunzio University |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 36 |
| Start date | 1 April 2026 |
| Primary completion | 31 July 2027 |
| Estimated completion | 31 July 2027 |
Drugs / interventions tested
- Non-Surgical Peri-Implant Therapy without Crown
- Non-Surgical Peri-Implant Therapy with Crown
Conditions studied
- Peri-implantitis — all drugs for Peri-implantitis →
Sponsor
G. d'Annunzio University
Who can join
18 and older, any sex, with Peri-implantitis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this single-blind, randomized controlled clinical trial is to evaluate whether removal of the prosthetic crown influences the clinical effectiveness of non-surgical mechanical therapy in implants affected by peri-implantitis. The study is designed to compare changes in several clinical and radiographic parameters between baseline and follow-up examinations at 3, 6, and 12 months. The primary outcome measure will be the mean peri-implant probing depth (PIPD). Secondary outcomes will include changes in gingival recession (REC), radiographic marginal bone level (MBL), modified bleeding index (mBI), and additional patient-related variables.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07391202
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Currently open trials in the same condition.
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Other G. d'Annunzio University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07391202 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by G. d'Annunzio University
- Last refreshed: 5 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07391202.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing