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NCT07388901
In Vivo Study on the Material Properties of iRoot SP and nRoot SP Root Canal Sealers
NA trial testing iRoot SP in Chronic Apical Periodontitis in 160 participants. Currently enrolling.
30 January 2027
Quick facts
| Lead sponsor | The Dental Hospital of Zhejiang University School of Medicine |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 160 |
| Start date | 27 May 2025 |
| Primary completion | 30 January 2027 |
| Estimated completion | 30 June 2027 |
| Sites | 1 location across China |
Drugs / interventions tested
- iRoot SP
- nRoot SP
Conditions studied
- Chronic Apical Periodontitis — all drugs for Chronic Apical Periodontitis →
Sponsor
The Dental Hospital of Zhejiang University School of Medicine
Who can join
18 and older, any sex, with Chronic Apical Periodontitis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
A randomized controlled trial was conducted to compare the treatment efficacy of iRoot SP and nRoot SP Root Canal Sealer Materials in patients with chronic apical periodontitis.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07388901
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Chronic Apical Periodontitis
Currently open trials in the same condition.
- NCT07069881 — Sonic vs Passive Ultrasonic Irrigation for Chronic Apical Periodontitis · NA · recruiting
- NCT07059481 — Effect of Different Root Canal Sealers on Oxidative Stress Markers · NA · recruiting
Other The Dental Hospital of Zhejiang University School of Medicine trials
Trials by the same sponsor.
- NCT07334067 — Site Preservation Was Performed Through an Open Healing Oral Restorative Membrane · NA · not yet recruiting
- NCT06449391 — The Application of Root Analogy Implant in Immediate Implantation · NA · recruiting
- NCT06031896 — The Severity of Periodontitis at the Buccal and Palatal Site · unknown
- NCT05275803 — Lactobacillus Reuteri for Non-surgical Periodontal Treatment of Chronic Periodontitis With Type 2 Diabetes Patients · NA · unknown
- NCT06318247 — Using Xenograft Combined With Barrier Membrane to Improve the Formation of Deep Periodontal Pockets · NA · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07388901 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by The Dental Hospital of Zhejiang University School of Medicine
- Last refreshed: 15 April 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07388901.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing