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NCT05275803
Lactobacillus Reuteri for Non-surgical Periodontal Treatment of Chronic Periodontitis With Type 2 Diabetes Patients
NA trial testing Probiotics in Periodontitis in 48 participants. Status unknown.
20 June 2023
Quick facts
| Lead sponsor | The Dental Hospital of Zhejiang University School of Medicine |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 48 |
| Start date | 8 June 2023 |
| Primary completion | 20 June 2023 |
| Estimated completion | 20 May 2024 |
Drugs / interventions tested
- Probiotics — full drug profile →
- Control
Conditions studied
- Periodontitis — all drugs for Periodontitis →
Sponsor
The Dental Hospital of Zhejiang University School of Medicine
Who can join
Adults 35 to 70, any sex, with Periodontitis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study aims to investigate the clinical and microbiological efficacy of Lactobacillus reuteri as an adjunctive therapy to non-surgical periodontal treatment of chronic periodontitis with type 2 diabetes.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Recent advances in therapeutic probiotics: insights from human trials.
Cho M-Y, Eom J-H, Choi E-M, Yang S-J, et al · · 2025 · cited 17× · PMID 40261032 · DOI 10.1128/cmr.00240-24
Verify or expand the search:
- PubMed search for NCT05275803
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other recruiting trials for Periodontitis
Currently open trials in the same condition.
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Other The Dental Hospital of Zhejiang University School of Medicine trials
Trials by the same sponsor.
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- NCT06449391 — The Application of Root Analogy Implant in Immediate Implantation · NA · recruiting
- NCT06031896 — The Severity of Periodontitis at the Buccal and Palatal Site · unknown
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05275803 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by The Dental Hospital of Zhejiang University School of Medicine
- Last refreshed: 7 June 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05275803.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing