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NCT07359183: LPEM
Long Term Outcomes Associated With Attainment of Remission Following Oral Immunotherapy to Peanut, Egg and Cow's Milk (LPEM Study)
trial in Food Allergies in 147 participants. Currently enrolling.
1 January 2027
Quick facts
| Lead sponsor | Murdoch Childrens Research Institute |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 147 |
| Start date | 13 January 2026 |
| Primary completion | 1 January 2027 |
| Estimated completion | 1 January 2027 |
| Sites | 1 location across Australia |
Conditions studied
- Food Allergies — all drugs for Food Allergies →
- Peanut Allergies — all drugs for Peanut Allergies →
- Egg Allergy — all drugs for Egg Allergy →
- Milk Allergy — all drugs for Milk Allergy →
Sponsor
Murdoch Childrens Research Institute
Who can join
Eligibility, any sex, with Food Allergies or Peanut Allergies. Patients with the condition only — healthy volunteers not accepted.
What's being measured
Primary outcomes are the specific endpoints the trial is designed to prove or disprove.
-
Changes in health-related quality of life (HRQL) scores from baseline to 5-15 years after stopping oral immunotherapy (OIT) in individuals who achieved remission and those who did not, as measured by Food Allergy Quality of Life Questionnaires (FAQLQ).
Time frame: A single study visit (approximately 2 hours) will be conducted at 5-15 years after the participant completed OIT in their parent study.
HRQL scores were collected via validated surveys (FAQLQ) during the parent studies (PEAT, PrEMO, PPOIT-001 and PPOIT-002), and will be used again in this study for comparison. Changes in HRQL scores from the parent study (baseline) to 5-15 years after stopping OIT will be compared between the clinical outcome groups (Allergic or Sustained Unresponsiveness (SU)/Remission), as determined by the clin
Sponsor's own description
The goal of this observational study is to learn about the long-term outcomes of children and young people who underwent an 18-month course of oral immunotherapy (OIT) treatment for peanut, egg or milk allergy. It aims to: • Compare long-term changes in health-related quality of life (HRQL) at 5-15 years after stopping OIT in participants who achieved remission and those who did not. Participants will attend a single follow-up visit for: * A blood test * Skin prick test (SPT) * Allergy questionnaires
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07359183
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Food Allergies
Currently open trials in the same condition.
- NCT06916819 — Food Challenge at Home or in Medical Practice - the FoodCHOMP Study · NA · recruiting
Other Murdoch Childrens Research Institute trials
Trials by the same sponsor.
- NCT07251790 — Optimising Breathing Support at Extubation in Very Preterm Infants: A Clinical Study · NA · not yet recruiting
- NCT07136584 — SOS for Caregiver Wellbeing · NA · recruiting
- NCT06686446 — Allergic Rhinitis Improvement Through Strategic Education: The ARISE Trial · NA · terminated
- NCT06992141 — A Strep Throat Controlled Human Infection Trial in Healthy Adults · EARLY_PHASE1 · completed
- NCT06186141 — Nausea and Vomiting in Postoperative Paediatric Patients With Patient-Controlled Analgesia (PCA): Morphine vs Oxycodone · Phase 4 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07359183 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Murdoch Childrens Research Institute
- Last refreshed: 29 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07359183.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing