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NCT07342374
Repositioning the Bolus Tracking ROI to the Superior Vena Cava in CTPA Facilitates Contrast Volume Reduction
NA trial testing Optimized CTPA Protocol in Pulmonary Artery Embolism in 72 participants. Completed in 16 December 2024.
16 December 2024
Quick facts
| Lead sponsor | Hospital Queen Elizabeth, Malaysia |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | diagnostic |
| Enrollment | 72 |
| Start date | 1 February 2023 |
| Primary completion | 16 December 2024 |
| Estimated completion | 16 December 2024 |
| Sites | 1 location across Malaysia |
Drugs / interventions tested
- Optimized CTPA Protocol
Conditions studied
- Pulmonary Artery Embolism — all drugs for Pulmonary Artery Embolism →
- Pulmonary Embolism (PE) — all drugs for Pulmonary Embolism (PE) →
Sponsor
Hospital Queen Elizabeth, Malaysia
Who can join
Adults 18 to 90, any sex, with Pulmonary Artery Embolism or Pulmonary Embolism (PE). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This randomized controlled trial evaluates a protocol optimization for Computed Tomography Pulmonary Angiography (CTPA). The study investigates the impact of repositioning the bolus-tracking region-of-interest (ROI) from the standard pulmonary trunk (PT) to the superior vena cava (SVC). The goal is to compensate for the CT scanner's inherent transit delay time (TDT) to better align the scan with the peak arterial phase. By optimizing this timing, the study assesses whether contrast media volume can be safely reduced by 40% (from 50 ml to 30 ml) while maintaining diagnostic image quality and preventing venous contamination.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07342374
- Europe PMC full search
- ASCO Meeting Library
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Related trials
Other Hospital Queen Elizabeth, Malaysia trials
Trials by the same sponsor.
- NCT04512196 — Surgical Site Infection in Perforated Appendicitis After Peritoneal Lavage With Super-oxidised Solution · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07342374 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Hospital Queen Elizabeth, Malaysia
- Last refreshed: 15 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07342374.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing