Last reviewed · How we verify

NCT07342374

Repositioning the Bolus Tracking ROI to the Superior Vena Cava in CTPA Facilitates Contrast Volume Reduction

Completed NA Last updated 15 January 2026
What this trial tests

NA trial testing Optimized CTPA Protocol in Pulmonary Artery Embolism in 72 participants. Completed in 16 December 2024.

Timeline
1 February 2023
Primary endpoint
16 December 2024
16 December 2024

Quick facts

Lead sponsorHospital Queen Elizabeth, Malaysia
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingsingle
Primary purposediagnostic
Enrollment72
Start date1 February 2023
Primary completion16 December 2024
Estimated completion16 December 2024
Sites1 location across Malaysia

Drugs / interventions tested

Conditions studied

Sponsor

Hospital Queen Elizabeth, Malaysia

Who can join

Adults 18 to 90, any sex, with Pulmonary Artery Embolism or Pulmonary Embolism (PE). Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This randomized controlled trial evaluates a protocol optimization for Computed Tomography Pulmonary Angiography (CTPA). The study investigates the impact of repositioning the bolus-tracking region-of-interest (ROI) from the standard pulmonary trunk (PT) to the superior vena cava (SVC). The goal is to compensate for the CT scanner's inherent transit delay time (TDT) to better align the scan with the peak arterial phase. By optimizing this timing, the study assesses whether contrast media volume can be safely reduced by 40% (from 50 ml to 30 ml) while maintaining diagnostic image quality and preventing venous contamination.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other Hospital Queen Elizabeth, Malaysia trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07342374.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing