NCT04512196 (PLaSSo) is a NA clinical trial of Superoxidized Water in Perforated Appendicitis, sponsored by Hospital Queen Elizabeth, Malaysia.

Who is sponsoring NCT04512196?

NCT04512196 is sponsored by Hospital Queen Elizabeth, Malaysia.

What drugs are being tested in NCT04512196?

Interventions in NCT04512196: Superoxidized Water, Normal Saline.

What condition does NCT04512196 study?

NCT04512196 studies Perforated Appendicitis.

Is NCT04512196 still recruiting?

NCT04512196 is currently completed. Last updated 25 May 2022.

Last reviewed 2022-05-25 · How we verify

NCT04512196: PLaSSo

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Surgical Site Infection in Perforated Appendicitis After Peritoneal Lavage With Super-oxidised Solution

Completed NA Last updated 25 May 2022

What this trial tests

NA trial testing Superoxidized Water in Perforated Appendicitis in 102 participants. Completed in 11 April 2022.

Timeline

9 September 2020

Primary endpoint
11 March 2022

11 April 2022

Quick facts

Lead sponsor	Hospital Queen Elizabeth, Malaysia
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	treatment
Enrollment	102
Start date	9 September 2020
Primary completion	11 March 2022
Estimated completion	11 April 2022
Sites	1 location across Malaysia

Drugs / interventions tested

Superoxidized Water — full drug profile →
Normal Saline

Conditions studied

Perforated Appendicitis — all drugs for Perforated Appendicitis →

Sponsor

Hospital Queen Elizabeth, Malaysia

Who can join

Adults 13 to 70, any sex, with Perforated Appendicitis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study is to evaluate the effectiveness of peritoneal lavage with super-oxidised solution in reducing surgical site infection after open surgery for perforated appendicitis.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Effect of peritoneal and wound lavage with super-oxidized solution on surgical-site infection after open appendicectomy in perforated appendicitis (PLaSSo): randomized clinical trial.
Sellappan H, Alagoo D, Loo C, Vijian K, et al · · 2024 · cited 4× · PMID 39413050 · DOI 10.1093/bjsopen/zrae121

Verify or expand the search:

Other recruiting trials for Perforated Appendicitis

Currently open trials in the same condition.

NCT06705842 — APPI-Cost Trial for Perforated Appendicitis · Phase 4 · recruiting
NCT06927765 — Effect of Intraperitoneal Drain Placement on Postoperative Outcomes Following Laparoscopic Appendectomy in Adult Patient · active not recruiting

Other Hospital Queen Elizabeth, Malaysia trials

Trials by the same sponsor.

NCT07342374 — Repositioning the Bolus Tracking ROI to the Superior Vena Cava in CTPA Facilitates Contrast Volume Reduction · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04512196 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Hospital Queen Elizabeth, Malaysia
Last refreshed: 25 May 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04512196.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing