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NCT07297459: OAADE
Arthroscopic Anterior Release Versus Discectomy as Treatments for Temporomandibular Joint Disc Displacement With Reduction
trial in TMJ - Injury of Meniscus of Temporomandibular Joint in 65 participants. Enrolling by invitation.
31 December 2027
Quick facts
| Lead sponsor | Karolinska Institutet |
|---|---|
| Status | ENROLLING BY INVITATION |
| Study type | OBSERVATIONAL |
| Enrollment | 65 |
| Start date | 16 September 2025 |
| Primary completion | 31 December 2027 |
| Estimated completion | 31 December 2027 |
| Sites | 1 location across Sweden |
Conditions studied
- TMJ - Injury of Meniscus of Temporomandibular Joint — all drugs for TMJ - Injury of Meniscus of Temporomandibular Joint →
- TMD — all drugs for TMD →
- TMJ - Oral &Amp;Maxillofacial Surgery — all drugs for TMJ - Oral &Amp;Maxillofacial Surgery →
Sponsor
Karolinska Institutet
Who can join
18 and older, any sex, with TMJ - Injury of Meniscus of Temporomandibular Joint or TMD. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this clinical trial is to compare and evalute the surgical intervention discectomy to arthroscopic anterior release due to the diagnosis temporomandibular joint disc displacement with reduction. The main questions it aims to answer are: * which of the two surgical methods that best improves maximum interincisal opening, temporomandibular joint pain, and temporomandibular joint function. * could any pre- or peri-operative variable/-s be identified as a predictor for outcome. * are there any differences in how fast the patient recover after anterior release and discectomy, respectively. * are there differences regarding postoperative hospitalisation, operating time, negative side effects? Researchers will compare the six-month surgical outcome regarding the above stated interventions. Study participants have already had their intervention, i.e. the study is retrospective.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07297459
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07297459 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Karolinska Institutet
- Last refreshed: 30 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07297459.
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