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NCT07292506: ACUPMIGRAINE
The Impact of Acupuncture on Biomarkers of Brain Injury and Inflammatory Response in Migraine
NA trial testing Standard acupuncture in Migraine in 75 participants. Participants enrolled and being followed up; not accepting new ones.
15 March 2026
Quick facts
| Lead sponsor | University Medical Centre Ljubljana |
|---|---|
| Phase | NA |
| Status | Active, enrolled |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 75 |
| Start date | 3 November 2025 |
| Primary completion | 15 March 2026 |
| Estimated completion | 15 July 2026 |
| Sites | 1 location across Slovenia |
Drugs / interventions tested
- Standard acupuncture
- Electroacupuncture
- Laser Acupuncture
Conditions studied
- Migraine — all drugs for Migraine →
- Migraine Headache — all drugs for Migraine Headache →
- Migraine Headache, With or Without Aura — all drugs for Migraine Headache, With or Without Aura →
- Migraine in Adults — all drugs for Migraine in Adults →
Sponsor
University Medical Centre Ljubljana
Who can join
Adults 18 to 85, any sex, with Migraine or Migraine Headache. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Migraine is more than just a headache-it can involve changes in the brain and inflammation. Recent research suggests that acupuncture may help by calming pain signals and reducing inflammation in the body. Scientists are studying whether acupuncture can also lower certain markers in the blood that show brain stress or inflammation. While more research is needed, acupuncture is considered safe and may reduce the number and severity of migraine attacks for many people. Acupuncture has been used for over 40 years in our practice to manage acute and chronic pain, including migraines. When performed by trained physicians, it is safe and typically reduces headache frequency and intensity, as well as nausea and vomiting, lowering the need for pain medication. Investigators are exploring three different ways to help manage migraine headaches using gentle stimulation techniques. These include laser acupuncture, electroacupuncture, and traditional acupuncture. Investigators want to see which method works best for reducing migraine symptoms. Investigators will look at how participants feel after treatment and also check blood samples for signs of inflammation and certain substances linked to migraines, such as calcitonin gene-related peptide (CGRP) and markers of brain stress. Investigators have a goal to find safe and effective options that can improve migraine care and help people feel better.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07292506
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07292506 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Medical Centre Ljubljana
- Last refreshed: 18 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07292506.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing