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NCT07290192
This Study Compares Two Different Ways of Cleaning and Shaping Root Canals During Root-canal Treatment: the Step-down Technique and the Step-back Technique. Iu Want to Find Out Which Method Causes Less Pain After the Procedure. Patients Will be Randomly Placed Into One of the Two Groups, Treated Wit
NA trial testing Step down technique in Pulp Necrosis in 110 participants. Not yet recruiting.
1 August 2026
Quick facts
| Lead sponsor | Armed Forces Post Graduate Medical Institute (AFPGMI), Rawalpindi |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | supportive care |
| Enrollment | 110 |
| Start date | 1 February 2026 |
| Primary completion | 1 August 2026 |
| Estimated completion | 1 February 2027 |
| Sites | 1 location across Pakistan |
Drugs / interventions tested
- Step down technique
Conditions studied
- Pulp Necrosis — all drugs for Pulp Necrosis →
Sponsor
Armed Forces Post Graduate Medical Institute (AFPGMI), Rawalpindi
Who can join
Adults 18 to 65, any sex, with Pulp Necrosis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This randomized clinical trial aims to compare the step-back and step-down root canal preparation techniques in patients with pulp necrosis. The study will evaluate which technique results in less postoperative pain. Participants will be randomly assigned to one of the two groups. Pain intensity will be recorded at specific time points after the procedure using a standardized pain scale. The goal is to identify the technique that provides better patient comfort after root canal treatment.This study is a randomized clinical trial designed to compare the effects of two root canal preparation techniques-step-back and step-down-on postoperative pain in patients diagnosed with pulp necrosis. Participants will be randomly assigned to one of the two groups.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07290192
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Pulp Necrosis
Currently open trials in the same condition.
- NCT07091981 — Effect of Rotary File Number on MB2 Canal Negotiation and Postoperative Pain · NA · recruiting
- NCT07391124 — In Vivo Pulp Thermal Changes During Different Slenderization Techniques · NA · active not recruiting
Other Armed Forces Post Graduate Medical Institute (AFPGMI), Rawalpindi trials
Trials by the same sponsor.
- NCT07275710 — Role of Alprazolam in Management of Post Endodontic Pain After Single Visit Root Canal Treatment. To Compare Mean Pain S · NA · not yet recruiting
- NCT05132712 — Effects of Angiotensin Converting Enzyme Inhibitors on Patency of Arterio-Venous Fistulas: A Randomized Controlled Trial · EARLY_PHASE1 · unknown
- NCT04994223 — Effectiveness of Combined Anticoagulation and Antithrombotic Therapy vs Antithrombotic Therapy Alone After Lower Extremi · EARLY_PHASE1 · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07290192 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Armed Forces Post Graduate Medical Institute (AFPGMI), Rawalpindi
- Last refreshed: 18 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07290192.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing