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NCT07261956
Lung Ultrasound for the Detection of Volume Overload in Patients With Severe Preeclampsia
NA trial testing Lung ultrasound in Pulmonary Edema - Acute in 202 participants. Currently enrolling.
31 December 2025
Quick facts
| Lead sponsor | Saint Thomas Hospital, Panama |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 202 |
| Start date | 25 August 2025 |
| Primary completion | 31 December 2025 |
| Estimated completion | 31 January 2026 |
| Sites | 1 location across Panama |
Drugs / interventions tested
- Lung ultrasound
Conditions studied
- Pulmonary Edema - Acute — all drugs for Pulmonary Edema - Acute →
- Preeclampsia — all drugs for Preeclampsia →
Sponsor
Saint Thomas Hospital, Panama
Who can join
Eligibility, female only, with Pulmonary Edema - Acute or Preeclampsia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This research aims to evaluate the usefulness of lung ultrasound (LUS) for detecting and monitoring fluid overload in patients with severe preeclampsia. Severe preeclampsia is a leading cause of maternal death and illness worldwide, often causing fluid buildup that can lead to a serious complication called pulmonary edema, especially after delivery. The study will be a prospective, longitudinal observational study with a diagnostic validation component. It will involve patients with a diagnosis of severe preeclampsia who meet specific inclusion criteria. Each participant will undergo a clinical exam and a lung ultrasound, which will assess eight zones of the lungs. The total number of B-lines-a sign of interstitial edema-will be documented. Data will be collected at three key times: upon admission, in the immediate postpartum period (within 24 hours of delivery), and 7-10 days postpartum. The results from the LUS will be compared to clinical signs like shortness of breath, rapid breathing, crackling sounds in the lungs, and oxygen saturation levels. The expected impact of this research is to provide evidence that LUS is a valuable, non-invasive, and accessible tool for the early detection of pulmonary congestion in patients with severe preeclampsia. This could lead to improved clinical decision-making and a reduction in maternal respiratory complications.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07261956
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Lung ultrasound
Trials testing the same drug.
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- NCT06555757 — Utilising AI Analysis of Sounds To prEdict heaRt failurE decOmpensation · not yet recruiting
Other Saint Thomas Hospital, Panama trials
Trials by the same sponsor.
- NCT06166303 — Number of Previous Cesarean Sections on the Results of Angiogenic Factors. · not yet recruiting
- NCT06122220 — Optic Nerve Sheath Measurement and Angiogenic Factors in Patients With Pre-eclampsia. · NA · recruiting
- NCT07265336 — Excess Base Comparison Between Pregnant Subjects With Severe Preeclampsia vs. Normotensive Pregnant Women · NA · recruiting
- NCT06123377 — Angiogenic Factors in the Conservative Management of Gestational Hypertension · NA · recruiting
- NCT06403722 — Perinatal Outcomes in Patients With Elevated sFlt-1/PlGF Ratio · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07261956 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Saint Thomas Hospital, Panama
- Last refreshed: 3 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07261956.
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