Optic Nerve Sheath Measurement and Angiogenic Factors in Patients With Pre-eclampsia.

NCT06122220 NA RECRUITING

Hypertensive disorders of pregnancy (HPT) are an important cause of maternal-feto-neonatal morbidity and mortality, being one of the three leading causes of maternal death in our country and in developing countries. The only cure for THE is termination of pregnancy, which ends up being a decision in which gestational age and maternal risks must be balanced. Angiogenic factors have come to occupy an indispensable place in the arsenal of tools that can be used to separate the patient with a high likelihood of complications from those in whom prolongation of pregnancy could represent an important neonatal benefit. Refining the diagnostic capability of this test would further improve maternal-fetal outcomes and the use of optic nerve sheath diameter (ONSD) measurement could make the difference. The purpose of the present study is to correlate the measurement of ONSD with serum angiogenic factor (AF) values in patients with pre-eclampsia and to determine its predictive ability for adverse perinatal outcomes.

Details

Lead sponsor	Saint Thomas Hospital, Panama
Phase	NA
Status	RECRUITING
Enrolment	200
Start date	Fri Aug 15 2025 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Fri Jan 30 2026 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

• Pre-Eclampsia

Interventions

• ONSD+AF

Countries

Panama