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NCT07254988
Gut Peptides and Bone Remodeling in Children With Neuromuscular Disorders
NA trial testing Meal test in Spinal Muscular Atrophy (SMA) in 3 participants. Terminated before completion.
1 December 2025
Quick facts
| Lead sponsor | University of Copenhagen |
|---|---|
| Phase | NA |
| Status | Terminated |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | single |
| Primary purpose | basic science |
| Enrollment | 3 |
| Start date | 24 March 2023 |
| Primary completion | 1 December 2025 |
| Estimated completion | 1 December 2025 |
| Sites | 1 location across Denmark |
Drugs / interventions tested
- Meal test
- GIP + GLP-2
- Placebo
Conditions studied
- Spinal Muscular Atrophy (SMA) — all drugs for Spinal Muscular Atrophy (SMA) →
- Cerebral Palsy (CP) — all drugs for Cerebral Palsy (CP) →
- Duchenne Muscular Dystrophy (DMD) — all drugs for Duchenne Muscular Dystrophy (DMD) →
Sponsor
University of Copenhagen
Who can join
Adults 10 to 17, any sex, with Spinal Muscular Atrophy (SMA) or Cerebral Palsy (CP). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Both GIP and GLP-2 reduce bone resorption (measured as CTX) in healthy adult individuals. In this study, we will investigate whether GIP and GLP-2 reduce CTX in children with spinal muscular atrophy, duchenne muscular dystrophy, or cerebral palsy.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07254988
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Other recruiting trials for Spinal Muscular Atrophy (SMA)
Currently open trials in the same condition.
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- NCT07265232 — Real World Clinical Effectiveness & Safety of Vesemnogene Lantuparvovec for Spinal Muscular Atrophy (SMA) in Low-middle · Phase 3 · recruiting
- NCT07223489 — Diagnostic Journey, Patient Experience, and Disparities in the Treatment of Spinal Muscular Atrophy (SMA) in the MedStar · recruiting
Other University of Copenhagen trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07254988 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Copenhagen
- Last refreshed: 16 April 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07254988.
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