Last reviewed · How we verify
NCT07245134: OCD-VRET1
Virtual Reality Exposure Therapy for Obsessive-Compulsive Disorder: A Randomized Controlled Trial in Inpatients
NA trial testing Exposure Therapy (Virtual Reality) in Obsessive-Compulsive Disorder in 62 participants. Currently enrolling.
30 December 2026
Quick facts
| Lead sponsor | National Institute of Mental Health, Czech Republic |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 62 |
| Start date | 15 November 2022 |
| Primary completion | 30 December 2026 |
| Estimated completion | 30 December 2026 |
| Sites | 1 location across Czechia |
Drugs / interventions tested
- Exposure Therapy (Virtual Reality)
- Cognitive flexibility training
- Standard CBT program without VR interventions
Conditions studied
- Obsessive-Compulsive Disorder — all drugs for Obsessive-Compulsive Disorder →
- Virtual Reality Exposure Therapy — all drugs for Virtual Reality Exposure Therapy →
- Virtual Reality Cognitive Training — all drugs for Virtual Reality Cognitive Training →
- Cognitive Behavior Therapy — all drugs for Cognitive Behavior Therapy →
Sponsor
National Institute of Mental Health, Czech Republic
Who can join
Adults 17 to 55, any sex, with Obsessive-Compulsive Disorder or Virtual Reality Exposure Therapy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this study is to evaluate the efficacy of virtual reality exposure therapy (VRET) as a treatment for obsessive-compulsive disorder (OCD). Participants are randomly assigned to one of the following interventions: a) exposure condition - the group with a standard CBT program enriched with exposure therapy in VR (VRET), b) control condition 1 - the group with a standard CBT program enriched with VR cognitive training aimed at cognitive flexibility or c) control condition 2 - standard CBT program without any additional VR intervention. The treatment effect will be evaluated using pre/post assessments, as well as monitoring adherence to exposure and response prevention assignments.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07245134
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Exposure Therapy (Virtual Reality)
Trials testing the same drug.
- NCT04975854 — Virtual Reality Exposure Therapy for Acrophobia · NA · completed
- NCT04737915 — Virtual Reality Exposure Versus In Vivo Exposure for Fear of Heights · NA · completed
Other recruiting trials for Obsessive-Compulsive Disorder
Currently open trials in the same condition.
- NCT06575075 — Pilot Study of RR-HNK in OCD · Phase 1, PHASE2 · recruiting
- NCT05783817 — MDMA-Assisted CBT for OCD (MDMA-CBT4OCD Study) · Phase 2 · recruiting
- NCT07065669 — Treating Adolescent Obsessive Compulsive Disorder With Transcranial Magnetic Stimulation · NA · recruiting
- NCT06376734 — Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness · Phase 2 · recruiting
- NCT07000812 — EEG Evaluation of CBT for Obsessive-Compulsive Disorder · NA · active not recruiting
Other National Institute of Mental Health, Czech Republic trials
Trials by the same sponsor.
- NCT07064629 — Training of Relaxation Breathing in Virtual Reality Using Biofeedback: Comparison Study · NA · enrolling by invitation
- NCT06915883 — Experiential and Relaxation Virtual Reality as a Tool for Easing Anxiety in Seriously Ill Children · NA · recruiting
- NCT07206199 — Virtual Reality Exposure Therapy for Obsessive-Compulsive Disorder: Outpatients Trial · NA · recruiting
- NCT04876144 — Kogito: App to Reduce Perinatal Psychosocial Stress · NA · unknown
- NCT04975854 — Virtual Reality Exposure Therapy for Acrophobia · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07245134 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National Institute of Mental Health, Czech Republic
- Last refreshed: 24 November 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07245134.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing