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NCT07232979
M-TAPA Block for Analgesia After Open-Heart Surgery
NA trial testing M TAPA block in Postoperative Pain in 80 participants. Not yet recruiting.
15 April 2026
Quick facts
| Lead sponsor | Bursa City Hospital |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 80 |
| Start date | 15 January 2026 |
| Primary completion | 15 April 2026 |
| Estimated completion | 15 April 2026 |
Drugs / interventions tested
- M TAPA block — full drug profile →
- Parasternal blocks — full drug profile →
- Local infiltration — full drug profile →
Conditions studied
- Postoperative Pain — all drugs for Postoperative Pain →
- Acute Pain — all drugs for Acute Pain →
Sponsor
Bursa City Hospital
Who can join
Adults 18 to 85, any sex, with Postoperative Pain or Acute Pain. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Postoperative pain following open-heart surgery is primarily caused by median sternotomy, although additional contributors include costovertebral joint stress related to sternal retraction and the presence of chest wall and mediastinal drains during the postoperative period. This pain is often severe, especially in the early postoperative hours, making effective management both challenging and essential. Insufficient pain control frequently necessitates high doses of opioids, which may lead to adverse effects such as nausea, vomiting, respiratory complications, and postoperative delirium. Excessive use of anesthetic agents or opioids can also delay extubation and prolong the process of weaning from mechanical ventilation. The modified thoracoabdominal nerve block through the perichondrial approach (M-TAPA) is a regional anesthesia technique performed beneath the costal margin between the internal oblique and transversus abdominis muscles. It provides broad dermatomal coverage, extending approximately from the upper thoracic to the lower thoracic and upper lumbar segments. This study aims to evaluate the postoperative analgesic effectiveness of combining the M-TAPA block with a parasternal block in patients undergoing open-heart surgery.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07232979
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of M TAPA block
Trials testing the same drug.
- NCT07311902 — M-Tapa Block and Transversus Abdominal Plane Block for Postoperative Analgesia in Unilateral Open Inguinal Hernia Repair · NA · recruiting
- NCT06660966 — Comparison Of M-TAPA Block and ESP Block İn Laparoscopic Cholesystektomy · NA · completed
- NCT05199922 — M-Tapa Block for Laparoscopic Inguinal Hernia Repair Surgery · NA · completed
- NCT05179629 — M-Tapa Block for Laparoscopic Cholesistectomy · NA · completed
Other recruiting trials for Postoperative Pain
Currently open trials in the same condition.
- NCT07452120 — DIPB vs. SIFIB for Postoperative Analgesia After Hip Surgery · NA · recruiting
- NCT07396688 — Comparative Evaluation of the Effects of Calcium Hydroxide and BIO-C Temp Medicaments on Postoperative Pain in Patients · NA · recruiting
- NCT07413055 — Comparative Efficacy Of 4 mg VS. 8 mg Submucosal Dexamethasone In Postoperative Pain Management After Dental Implant Sur · Phase 3 · recruiting
- NCT07496086 — External Oblique Intercostal Block Versus Transversus Abdominis Plane Combined With Rectus Sheath Block on Postoperative · NA · recruiting
- NCT07396545 — External Oblique Intercostal Block Versus Erector Spinae Plane Block on Postoperative Pain in Laparoscopic Radical Gastr · NA · recruiting
Other Bursa City Hospital trials
Trials by the same sponsor.
- NCT06925256 — Considering Peripheral Nerve Injury, Is It Safe to Perform Transradial Angiography? · NA · not yet recruiting
- NCT07480278 — mTLIP vs QIPB for Postoperative Analgesia in Lumbar Microdiscectomy Surgery · NA · recruiting
- NCT07482345 — Impact of Different Fasting Strategies on Gastric Ultrasound and Anxiety Levels in Children · NA · not yet recruiting
- NCT07370415 — mTLIP vs QIPB for Postoperative Analgesia After Lumbar Instrumentation Surgery · NA · not yet recruiting
- NCT07410000 — Ultrasound-Guided Quadro-Iliac Plane Block for Pain Management After Total Hip Arthroplasty · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07232979 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Bursa City Hospital
- Last refreshed: 19 November 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07232979.
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