Who is sponsoring NCT07228286?

NCT07228286 is sponsored by Samuel Snider, MD.

What drugs are being tested in NCT07228286?

Interventions in NCT07228286: Deep brain stimulation (DBS) electrode implantation.

What condition does NCT07228286 study?

NCT07228286 studies Disorders of Consciousness.

Is NCT07228286 still recruiting?

NCT07228286 is currently recruiting now. Last updated 14 November 2025.

Last reviewed 2025-11-14 · How we verify

NCT07228286

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

REstoring CONsciousness With NEurostimulation of the Central Thalamus: The RECONNECT Study

Recruiting now EARLY_PHASE1 Last updated 14 November 2025

What this trial tests

EARLY_PHASE1 trial testing Deep brain stimulation (DBS) electrode implantation in Disorders of Consciousness in 2 participants. Currently enrolling.

Timeline

10 November 2025

Primary endpoint
10 February 2029

10 February 2029

Quick facts

Lead sponsor	Samuel Snider, MD
Phase	EARLY_PHASE1
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	non randomized
Design	crossover
Masking	double
Primary purpose	device feasibility
Enrollment	2
Start date	10 November 2025
Primary completion	10 February 2029
Estimated completion	10 February 2029
Sites	1 location across United States

Drugs / interventions tested

Deep brain stimulation (DBS) electrode implantation

Conditions studied

Disorders of Consciousness — all drugs for Disorders of Consciousness →

Sponsor

Samuel Snider, MD

Who can join

Adults 18 to 55, any sex, with Disorders of Consciousness. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The RE-CONNECT study is an early feasibility study to establish the safety, feasibility, and efficacy of two central thalamic deep brain stimulation targets in patients with chronic disorders of consciousness.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other recruiting trials for Disorders of Consciousness

Currently open trials in the same condition.

NCT06959212 — Investigation of Mnesic Capacities in Patients With a Disorder of Consciousness · NA · recruiting
NCT06851156 — Transcranial Temporal Interference Stimulation In Severely Brain Injured Patients With Disorders of Consciousness · NA · recruiting
NCT06464549 — Spontaneous Eye Blinking Evaluation for Cognitive Assessment of Individuals With Severe Acquired Brain Injury · active not recruiting
NCT07284732 — Effect of Transcutaneous Auricular Vagus Nerve Stimulation on Patients With Disorders of Consciousness · NA · recruiting
NCT06922162 — Tickle Stimulation in Disorders of Consciousness (DoC) · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT07228286 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Samuel Snider, MD
Last refreshed: 14 November 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07228286.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing