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NCT06922162: TICKLING-DOC
Tickle Stimulation in Disorders of Consciousness (DoC)
trial testing Tickle stimulation in Disorders of Consciousness in 45 participants. Currently enrolling.
31 July 2025
Quick facts
| Lead sponsor | Anna Estraneo |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 45 |
| Start date | 30 June 2023 |
| Primary completion | 31 July 2025 |
| Estimated completion | 31 October 2025 |
| Sites | 2 locations across Belgium, Italy |
Drugs / interventions tested
- Tickle stimulation
- Neurophysiological Monitoring with SedLine
Conditions studied
- Disorders of Consciousness — all drugs for Disorders of Consciousness →
Sponsor
Anna Estraneo
Who can join
18 and older, any sex, with Disorders of Consciousness. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this project is to investigate whether tickling stimulations can have a short-term effect on the responsiveness of patients with Disorders of Consciousness due to Severe Acquired Brain Injury and to compare this effect with that of neutral tactile stimulations that do not induce tickling.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06922162
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Disorders of Consciousness
Currently open trials in the same condition.
- NCT07228286 — REstoring CONsciousness With NEurostimulation of the Central Thalamus: The RECONNECT Study · EARLY_PHASE1 · recruiting
- NCT06959212 — Investigation of Mnesic Capacities in Patients With a Disorder of Consciousness · NA · recruiting
- NCT06851156 — Transcranial Temporal Interference Stimulation In Severely Brain Injured Patients With Disorders of Consciousness · NA · recruiting
- NCT06464549 — Spontaneous Eye Blinking Evaluation for Cognitive Assessment of Individuals With Severe Acquired Brain Injury · active not recruiting
- NCT07284732 — Effect of Transcutaneous Auricular Vagus Nerve Stimulation on Patients With Disorders of Consciousness · NA · recruiting
Other Anna Estraneo trials
Trials by the same sponsor.
- NCT06469983 — Robotic vs. Traditional Verticalization in Patients With Severe Acquired Brain Injury: a Randomized Controlled Trial · NA · recruiting
- NCT06474871 — Virtual Reality vs Traditional Cognitive Training in Patients With Severe Acquired Brain Injury · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06922162 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Anna Estraneo
- Last refreshed: 23 April 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06922162.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing