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NCT07212504: NACC-EC
Effect of Accelerated Neuromodulation of Anterior Cingulate Cortex to Enhance Cognition in Older Adults With Mild Memory Problems
NA trial testing Active Brainsway H7-Coil Deep TMS System in Mild Cognitive Impairment (MCI) in 30 participants. Currently enrolling.
15 March 2027
Quick facts
| Lead sponsor | Rotman Research Institute at Baycrest |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 30 |
| Start date | 15 November 2025 |
| Primary completion | 15 March 2027 |
| Estimated completion | 15 March 2027 |
| Sites | 1 location across Canada |
Drugs / interventions tested
- Active Brainsway H7-Coil Deep TMS System
- Sham Brainsway H1-Coil Deep TMS System
Conditions studied
- Mild Cognitive Impairment (MCI) — all drugs for Mild Cognitive Impairment (MCI) →
- Subjective Cognitive Decline (SCD) — all drugs for Subjective Cognitive Decline (SCD) →
Sponsor
Rotman Research Institute at Baycrest
Who can join
Adults 55 to 85, any sex, with Mild Cognitive Impairment (MCI) or Subjective Cognitive Decline (SCD). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this clinical trial is to test whether an accelerated deep Transcranial Magnetic Stimulation (dTMS) protocol in combination with cognitive training can improve cognitive abilities in older adults with Subjective Cognitive Decline (SCD) or Mild Cognitive Impairment (MCI). The study will look at whether it is safe and tolerable to use accelerated dTMS to enhance the benefits of cognitive training in older adults, and will also gather early information on the effects of accelerated dTMS on memory and other cognitive abilities.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07212504
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Active Brainsway H7-Coil Deep TMS System
Trials testing the same drug.
- NCT07212465 — Accelerated Neuromodulation of Anterior Cingulate Cortex for Depression · NA · recruiting
- NCT06095063 — dTMS for Subjective Cognitive Decline · NA · recruiting
Other recruiting trials for Mild Cognitive Impairment (MCI)
Currently open trials in the same condition.
- NCT07516119 — Predicting Pre-dementia · recruiting
- NCT07526740 — Brain Stimulation and Cognitive Training for MCI · NA · recruiting
- NCT07101380 — Feasibility Study of 'SuperBrain BOOM' for Mild Cognitive Impairment Patients · NA · recruiting
- NCT07420426 — Instant Message-delivered Personalised Acceptance and Commitment Therapy (IMPACT) for Neuropsychiatric Symptoms in Perso · NA · recruiting
- NCT07286448 — Personalized Digital Training for COGnitive FITness in Mild Cognitive Impairment · NA · recruiting
Other Rotman Research Institute at Baycrest trials
Trials by the same sponsor.
- NCT07212465 — Accelerated Neuromodulation of Anterior Cingulate Cortex for Depression · NA · recruiting
- NCT06095063 — dTMS for Subjective Cognitive Decline · NA · recruiting
- NCT05076045 — Effects of PSAPs on Speech Processing · NA · completed
- NCT04623125 — Spaced Retrieval as Treatment for Aphasia · NA · completed
- NCT03665831 — Deep TMS for Comorbid Depression and Cognitive Impairment in Older Adults · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07212504 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Rotman Research Institute at Baycrest
- Last refreshed: 28 October 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07212504.
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