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NCT07193836: Li
Synergistic Effect of Intravenous Lidocaine on Anesthetic Induction and Emergence in Patients Undergoing Laparoscopic Cholecystectomy or Gynecological Surgery
NA trial testing Normal Saline (0.9% NaCl) in Cholecystectomy, Laparoscopic in 195 participants. Enrolling by invitation.
31 December 2025
Quick facts
| Lead sponsor | General Hospital of Ningxia Medical University |
|---|---|
| Phase | NA |
| Status | ENROLLING BY INVITATION |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 195 |
| Start date | 25 September 2025 |
| Primary completion | 31 December 2025 |
| Estimated completion | 31 December 2025 |
| Sites | 1 location across China |
Drugs / interventions tested
- Normal Saline (0.9% NaCl) — full drug profile →
- Lidocaine — full drug profile →
- Lidocaine Bolus + Infusion — full drug profile →
Conditions studied
- Cholecystectomy, Laparoscopic — all drugs for Cholecystectomy, Laparoscopic →
- Gynecologic Surgical Procedures — all drugs for Gynecologic Surgical Procedures →
- Anesthesia and Procedure Related Time Intervals — all drugs for Anesthesia and Procedure Related Time Intervals →
Sponsor
General Hospital of Ningxia Medical University
Who can join
Adults 18 to 70, any sex, with Cholecystectomy, Laparoscopic or Gynecologic Surgical Procedures. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study aims to evaluate the effect of intravenous lidocaine on consciousness changes during anesthesia in patients undergoing laparoscopic cholecystectomy or gynecologic surgery. A total of 150 patients will be randomly assigned to one of three groups: a single-dose lidocaine group, a continuous-infusion group, or a placebo group. All patients will receive standard anesthesia care, and the study will monitor brain activity using EEG-based PSi values to measure anesthesia induction time, recovery time, and changes in consciousness. The goal is to determine whether lidocaine can reduce the amount of anesthetic used, shorten the time to fall asleep, and promote faster awakening after surgery. The results may help improve anesthesia safety and enhance recovery in surgical patients.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07193836
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07193836 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by General Hospital of Ningxia Medical University
- Last refreshed: 26 September 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07193836.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing