Last reviewed · How we verify
NCT07171632
Components of Mechanical Power on the Functional Lung in ARDS
trial testing monitoring of clinical and ventilatory variables in Respiratory Distress Syndrome (RDS) in 184 participants. Not yet recruiting.
1 December 2026
Quick facts
| Lead sponsor | Ramos Mejía Hospital |
|---|---|
| Status | Not yet recruiting |
| Study type | OBSERVATIONAL |
| Enrollment | 184 |
| Start date | 1 December 2025 |
| Primary completion | 1 December 2026 |
| Estimated completion | 10 March 2027 |
Drugs / interventions tested
- monitoring of clinical and ventilatory variables
Conditions studied
- Respiratory Distress Syndrome (RDS) — all drugs for Respiratory Distress Syndrome (RDS) →
Sponsor
Ramos Mejía Hospital
Who can join
18 and older, any sex, with Respiratory Distress Syndrome (RDS). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Mechanical power (MP) is a composite variable that integrates static and dynamic respiratory parameters and has been associated with ventilator-induced lung injury (VILI). MP is predominantly delivered to the reduced functional lung size, commonly referred to as the "baby lung" (BL). Functional lung size, in turn, is closely related to respiratory system compliance (Crs). Previous studies have demonstrated an association between MP normalized to compliance (MP/Crs) and mortality. Moreover, evidence suggests that VILI associated with MP/Crs results primarily from the combined effect of its components rather than from any single component in isolation. The objective of this study is to evaluate both the overall and the relative contribution of each component of mechanical power, normalized to compliance (MP/Crs), to in-hospital mortality in patients with acute respiratory distress syndrome (ARDS).
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07171632
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Respiratory Distress Syndrome (RDS)
Currently open trials in the same condition.
- NCT06966752 — Comparison of Continuous Positive Airway Pressure (CPAP) and Non-Invasive Positive Pressure Ventilation (NIPPV) in Prete · NA · recruiting
- NCT06774534 — SerpinB3 Expression, PAR2 and SCCA-PD Polymorphism in Acute Respiratory Distress Syndrome · recruiting
- NCT06758492 — A Prospective Observational Study of Video Laryngoscopy Versus Direct Laryngoscopy for Insertion of a Thin Endotracheal · recruiting
Other Ramos Mejía Hospital trials
Trials by the same sponsor.
- NCT06192342 — Ventilatory Parameters in Acute Neurological Injury · recruiting
- NCT05248243 — Recruitment Assessment in Patients With Acute Respiratory Distress Syndrome and Covid-19 · unknown
- NCT05761626 — Mechanical Power Normalized to Compliance in ARDS · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07171632 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ramos Mejía Hospital
- Last refreshed: 4 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07171632.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing