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NCT07151742
Effects of Intradialytic Exercise on Muscle Oxygenation and Dialysis Adequacy
NA trial testing EXERCISE TRAINING WITH OR WITHOUT MEDICATION in Chronic Kidney Disease, Stage 5 in 40 participants. Enrolling by invitation.
25 November 2025
Quick facts
| Lead sponsor | Istinye University |
|---|---|
| Phase | NA |
| Status | ENROLLING BY INVITATION |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 40 |
| Start date | 25 May 2025 |
| Primary completion | 25 November 2025 |
| Estimated completion | 15 December 2025 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- EXERCISE TRAINING WITH OR WITHOUT MEDICATION — full drug profile →
Conditions studied
- Chronic Kidney Disease, Stage 5 — all drugs for Chronic Kidney Disease, Stage 5 →
- Sarcopenia — all drugs for Sarcopenia →
Sponsor
Istinye University
Who can join
Adults 18 to 65, any sex, with Chronic Kidney Disease, Stage 5 or Sarcopenia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This randomized controlled trial will evaluate the effects of a 12-week intradialytic combined exercise program, consisting of aerobic and resistance training, in patients with stage 5 chronic kidney disease receiving maintenance hemodialysis. Sarcopenia, a progressive loss of muscle mass and strength, is common in this population due to chronic disease burden and the sedentary nature of dialysis sessions. The intervention group will perform structured exercise three times per week during the first two hours of dialysis, while the control group will continue routine dialysis care without exercise. The primary aim is to investigate whether intradialytic exercise can improve dialysis adequacy and muscle oxygenation, and reduce sarcopenia severity. Secondary objectives include evaluating changes in physical performance, muscle strength, fatigue levels, and health-related quality of life. Approximately 40 participants will be randomized into intervention and control groups. Outcomes will be assessed through clinical measurements, functional tests, and patient-reported questionnaires before and after the intervention period.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07151742
- Europe PMC full search
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07151742 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Istinye University
- Last refreshed: 3 September 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07151742.
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