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NCT07144969
Chewing Gum vs Honey in Postoperative Recovery After Ileostomy Reversal: A Study Comparing Their Effects on Bowel Function, Complications, and Hospital Stay
NA trial testing Honey in Ileostomy Closure in 60 participants. Completed in 30 November 2024.
31 October 2024
Quick facts
| Lead sponsor | Mayo Hospital Lahore |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | supportive care |
| Enrollment | 60 |
| Start date | 1 February 2024 |
| Primary completion | 31 October 2024 |
| Estimated completion | 30 November 2024 |
| Sites | 1 location across Pakistan |
Drugs / interventions tested
- Honey — full drug profile →
- gum chewing — full drug profile →
Conditions studied
- Ileostomy Closure — all drugs for Ileostomy Closure →
- Gum Chewing — all drugs for Gum Chewing →
- Honey — all drugs for Honey →
- Postoperative Recovery — all drugs for Postoperative Recovery →
Sponsor
Mayo Hospital Lahore
Who can join
18 and older, any sex, with Ileostomy Closure or Gum Chewing. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Title: Comparison of the effect of chewing gum and honey on postoperative recovery and complications in ileostomy reversal - a pilot randomized controlled trial Background: Ileostomy reversal is associated with postoperative complications such as ileus, delayed gastrointestinal function recovery (GIFR), and infections. Chewing gum (sham feeding) and honey have been proposed as cost-effective interventions to enhance recovery, but their comparative efficacy remains underexplored. Objective: To evaluate the effects of chewing gum versus honey on postoperative recovery and complications in patients undergoing ileostomy reversal. Methods: A prospective single-blinded pilot randomized controlled trial is to be conducted at Mayo Hospital, Lahore, involving 30 patients (15 per group). Group A received chewing gum, while Group B received honey, starting 24 hours postoperatively. Primary outcomes included time to bowel sounds, flatus, and feces. Secondary outcomes were time to full feeds, intraabdominal infections, postoperative ileus, nausea/vomiting, and length of hospital stay. Data significance was set at p \< 0.05.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
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Other Mayo Hospital Lahore trials
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07144969 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Mayo Hospital Lahore
- Last refreshed: 28 August 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07144969.
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