Who is sponsoring NCT07114016?

NCT07114016 is sponsored by Future University in Egypt.

What drugs are being tested in NCT07114016?

Interventions in NCT07114016: Glucosamine Hydrochloride, Triamcinolone Acetonide.

What condition does NCT07114016 study?

NCT07114016 studies Oral Lichen Planus.

Is NCT07114016 still recruiting?

NCT07114016 is currently completed. Last updated 17 August 2025.

Last reviewed 2025-08-17 · How we verify

NCT07114016

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Efficacy of Topical Glucosamine Versus Corticosteroid in Oral Lichen Planus

Completed Phase 4 Last updated 17 August 2025

What this trial tests

Phase 4 trial testing Glucosamine Hydrochloride in Oral Lichen Planus in 36 participants. Completed in 31 July 2025.

Timeline

1 May 2023

Primary endpoint
15 May 2025

31 July 2025

Quick facts

Lead sponsor	Future University in Egypt
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	36
Start date	1 May 2023
Primary completion	15 May 2025
Estimated completion	31 July 2025
Sites	1 location across Egypt

Drugs / interventions tested

Glucosamine Hydrochloride — full drug profile →
Triamcinolone Acetonide — full drug profile →

Conditions studied

Oral Lichen Planus — all drugs for Oral Lichen Planus →

Sponsor

Future University in Egypt

Who can join

Adults 25 to 60, any sex, with Oral Lichen Planus. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Glucosamine (GlcN) is an N-deacetyl amino sugar derived from the complete hydrolysis of chitosan. It is classified as a nutraceutical and it is used mainly orally for the therapy of osteoarthritis since GlcN has immunoregulatory capacity and anti-inflammatory effects. Given the Oral lichen planus (OLP) T-cell-mediated pathogenesis; this drug seems to be a promising therapeutic option. The investigators compared the clinical efficacy of topical glucosamine to topical corticosteroid in the treatment of symptomatic OLP and investigated the effect of these two treatment modalities on the expression of tumor necrosis factor-alpha (TNF-α) in oral lichen planus lesions

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Chitosan-Based Drug Delivery Systems for Targeted Chemotherapy in Colorectal Cancer: A Scoping Review.
Piotrowska U, Szatko J, Nowakowska A, Klimaszewska E, et al · · 2025 · PMID 41440901 · DOI 10.3390/md23120467

Verify or expand the search:

Other recruiting trials for Oral Lichen Planus

Currently open trials in the same condition.

NCT06981767 — Effect of Topical Bromelain Versus Topical Corticosteroids in the Management of Oral Lichen Planus · Phase 2 · recruiting
NCT07131813 — Evaluation of Efficacy and Safety of add-on Tofacitinib in Patients With Oral Lichen Planus · Phase 4 · recruiting
NCT06932848 — The Therapeutic Effect of Curcumin in Nanogels Compared to 0.1% FAO in the Management of Oral Lichen Planus · NA · recruiting
NCT07100613 — Mucoadhesive Modified-Release Formulations for the Topical Treatment of Symptomatic Oral Lichen Planus · Phase 2 · recruiting
NCT06233591 — Evaluating LP-10 in Subjects With OLP · Phase 2 · active not recruiting

Other Future University in Egypt trials

Trials by the same sponsor.

NCT07347925 — Effect of Pre-Hospital ARNI Therapy on Short-Term Outcomes in HFrEF · recruiting
NCT07129720 — Educational Program to Improve Dental Interns, Knowledge ,Attitude and Awareness Toward Molar Incisor Hypo-mineralizatio · NA · completed
NCT07193342 — Effect of Computer-controlled vs. Conventional Injection on Pain and Anxiety in Children · NA · completed
NCT06950762 — Aesthetic Performance of Two Injectable Resin Composites in Class V Cavities: A Randomized Clinical Trial · NA · not yet recruiting
NCT06882343 — Performance of Bioactive Low Viscosity Composite in Deep Marginal Elevation Restorations · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT07114016 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Future University in Egypt
Last refreshed: 17 August 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07114016.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing