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Triamcinolone acetonide injection
Triamcinolone acetonide injection is a Corticosteroid Small molecule drug developed by Somdech Phra Nangchao Sirikit Hospital. It is currently FDA-approved for Inflammatory and allergic conditions, Rheumatoid arthritis and other autoimmune disorders, Dermatological conditions (lichen planus, psoriasis). Also known as: control group, Triamcinolone Acetonide, Epirelefan.
Triamcinolone acetonide is a synthetic corticosteroid that suppresses the immune system and reduces inflammation by binding to glucocorticoid receptors.
Triamcinolone acetonide is a synthetic corticosteroid that suppresses the immune system and reduces inflammation by binding to glucocorticoid receptors. Used for Inflammatory and allergic conditions, Rheumatoid arthritis and other autoimmune disorders, Dermatological conditions (lichen planus, psoriasis).
At a glance
| Generic name | Triamcinolone acetonide injection |
|---|---|
| Also known as | control group, Triamcinolone Acetonide, Epirelefan |
| Sponsor | Somdech Phra Nangchao Sirikit Hospital |
| Drug class | Corticosteroid |
| Target | Glucocorticoid receptor |
| Modality | Small molecule |
| Therapeutic area | Immunology, Rheumatology, Dermatology |
| Phase | FDA-approved |
Mechanism of action
Triamcinolone acetonide works by entering cells and binding to intracellular glucocorticoid receptors, which then translocate to the nucleus and modulate gene expression. This leads to decreased production of pro-inflammatory cytokines, reduced immune cell activation and migration, and suppression of inflammatory mediators. The injectable formulation allows for localized or systemic anti-inflammatory and immunosuppressive effects depending on the route of administration.
Approved indications
- Inflammatory and allergic conditions
- Rheumatoid arthritis and other autoimmune disorders
- Dermatological conditions (lichen planus, psoriasis)
- Respiratory conditions (asthma, COPD)
- Adrenocortical insufficiency
Common side effects
- Hyperglycemia
- Hypertension
- Osteoporosis (with chronic use)
- Immunosuppression/increased infection risk
- Adrenal suppression
- Mood changes
- Insomnia
- Local injection site reactions
Key clinical trials
- Dose Dependent Steroid Injections (PHASE4)
- A Norwegian Trial Comparing Treatment Strategies for Carpal Tunnel Syndrome (PHASE4)
- Evolution of Post-Stroke Shoulder Pain With a Capsular Pattern With Physiotherapy Alone Versus Coupled With Mild Arthrographic Distension With Cortisone (PHASE4)
- USG-Guided Shoulder Injections in Frozen Shoulder (NA)
- Local Methotrexate Injections for the Treatment of Nail Psoriasis (PHASE4)
- Corticosteroid Meniscectomy Randomized Trial (PHASE4)
- Triamcinolone Acetonide Injection for Upper Eyelid Retraction in Thyroid Eye Disease (NA)
- Use of Steroid Injections to Prevent the Recurrence of Tracheal Stenosis in Idiopathic Subglottic Stenosis (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Triamcinolone acetonide injection CI brief — competitive landscape report
- Triamcinolone acetonide injection updates RSS · CI watch RSS
- Somdech Phra Nangchao Sirikit Hospital portfolio CI
Frequently asked questions about Triamcinolone acetonide injection
What is Triamcinolone acetonide injection?
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Is Triamcinolone acetonide injection also known as anything else?
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Related
- Drug class: All Corticosteroid drugs
- Target: All drugs targeting Glucocorticoid receptor
- Manufacturer: Somdech Phra Nangchao Sirikit Hospital — full pipeline
- Therapeutic area: All drugs in Immunology, Rheumatology, Dermatology
- Indication: Drugs for Inflammatory and allergic conditions
- Indication: Drugs for Rheumatoid arthritis and other autoimmune disorders
- Indication: Drugs for Dermatological conditions (lichen planus, psoriasis)
- Also known as: control group, Triamcinolone Acetonide, Epirelefan
- Compare: Triamcinolone acetonide injection vs similar drugs
- Pricing: Triamcinolone acetonide injection cost, discount & access