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NCT07108413: Activ4Brain
Study of the Cognitive and Neurophysiological Effects of the Activ4Brain Program for Older Adults
NA trial testing Activ4Brain Program in Older People in 72 participants. Completed in 30 March 2025.
30 March 2025
Quick facts
| Lead sponsor | University of Coimbra |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | supportive care |
| Enrollment | 72 |
| Start date | 1 January 2024 |
| Primary completion | 30 March 2025 |
| Estimated completion | 30 March 2025 |
| Sites | 1 location across Portugal |
Drugs / interventions tested
- Activ4Brain Program
- Aerobic Exercise Program
Conditions studied
- Older People — all drugs for Older People →
Sponsor
University of Coimbra
Who can join
Adults 55 to 75, any sex, with Older People. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study aims to examine the cognitive, neuronal, and physical effects of the Activ4Brain program in older men and women between 55 and 75 years of age. The program Activ4Brain consists of 24 sessions of aerobic exercise classes (twice a week over 3 months) that include computerized games designed to train cognition. Participants are tested before and after the 3-months intervention. Researchers will study changes in cognitive function, brain and body physiological activity, and inflammation and neuroprotective markers in 3 groups of participants: the Activ4Brain group that engages in the Activ4Brain program, an active control group that engages in aerobic exercise classes and a passive control group that does not engage in any intervention. This study aims to answer the following questions. * Does the program Activ4Brain improve cognition in cognitively healthy older adults? * Does the program Activ4Brain change brain function and body physiology in cognitively healthy older adults?
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07108413
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07108413 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Coimbra
- Last refreshed: 7 August 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07108413.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing