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NCT07100457
OR6A2 on Monocytes and Cardiovascular Outcomes in Myocardial Ischemia-Reperfusion Injury
trial testing Blood Biomarker Profiling and Prognostic Follow-up in Myocardial Ischemia-Reperfusion Injury in 200 participants. Currently enrolling.
30 August 2027
Quick facts
| Lead sponsor | Southeast University, China |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 200 |
| Start date | 1 September 2019 |
| Primary completion | 30 August 2027 |
| Estimated completion | 30 August 2027 |
| Sites | 1 location across China |
Drugs / interventions tested
- Blood Biomarker Profiling and Prognostic Follow-up
Conditions studied
- Myocardial Ischemia-Reperfusion Injury — all drugs for Myocardial Ischemia-Reperfusion Injury →
Sponsor
Southeast University, China
Who can join
Adults 18 to 90, any sex, with Myocardial Ischemia-Reperfusion Injury. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study examines how the interaction between octanal (an OR6A2 receptor activator) and OR6A2 expression influences inflammation and clinical outcomes in Myocardial Ischemia-Reperfusion Injury patients. We analyze two key relationships: 1) The octanal-OR6A2 pathway's association with systemic oxidative stress/inflammatory biomarkers, and 2) How OR6A2 expression patterns on monocyte subtypes and plasma octanal levels correlate with major cardiovascular events. Patients undergoing this post-revascularization injury provided blood samples for OR6A2/octanal/inflammation measurements. IR Injury patients underwent 44-month clinical follow-up. Results may identify biological markers for personalized risk assessment after revascularization therapies. Ethics approval: Zhongda Hospital #2020ZDSYLL051-P01.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07100457 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Southeast University, China
- Last refreshed: 3 August 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07100457.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing