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NCT07098611: REXs
A New Tool for Extubation Readiness in Mechanically Ventilated Patients: Readiness for EXtubation Score
trial in Ventilator Weaning in 470 participants. Currently enrolling.
30 December 2026
Quick facts
| Lead sponsor | Medipol University |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 470 |
| Start date | 15 June 2025 |
| Primary completion | 30 December 2026 |
| Estimated completion | 30 December 2026 |
| Sites | 7 locations across Italy, Turkey (Türkiye), Chile, Iran, Egypt, Spain |
Conditions studied
- Ventilator Weaning — all drugs for Ventilator Weaning →
- Respiration, Artificial — all drugs for Respiration, Artificial →
- Respiratory Failure — all drugs for Respiratory Failure →
- Extubation Readiness — all drugs for Extubation Readiness →
Sponsor
Medipol University
Who can join
Adults 18 to 89, any sex, with Ventilator Weaning or Respiration, Artificial. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Liberation from mechanical ventilation involves three steps: weaning, readiness assessment, and extubation. Readiness is determined using clinical criteria such as improvement of the underlying condition, hemodynamic stability, and adequate respiratory effort. Successful extubation is defined as not requiring invasive support within 48 hours. Due to the complexity of ICU patients, various clinical parameters and multi-component scores have been developed to predict extubation success. This study aims to develop and evaluate a multi-component score, the Readiness for EXtubation score (REXs), to predict extubation readiness in ICU patients under invasive mechanical ventilation.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07098611
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Ventilator Weaning
Currently open trials in the same condition.
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Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07098611 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Medipol University
- Last refreshed: 21 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07098611.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing