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NCT07090083
Pediatric Metabolic Dysfunction-associated Steatotic Liver Disease and Food Insecurity
trial in MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease in 160 participants. Currently enrolling.
30 December 2026
Quick facts
| Lead sponsor | University of California, San Francisco |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 160 |
| Start date | 30 July 2025 |
| Primary completion | 30 December 2026 |
| Estimated completion | 30 December 2026 |
| Sites | 1 location across United States |
Conditions studied
- MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease — all drugs for MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease →
- Food Insecurity — all drugs for Food Insecurity →
Sponsor
University of California, San Francisco
Who can join
Adults 6 to 17, any sex, with MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease or Food Insecurity. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This proposal addresses a critical gap in our understanding of the impact of household food insecurity (FI) on pediatric metabolic dysfunction-associated steatotic liver disease (MASLD) severity. There is evidence that children in families that do not have the ability to provide consistently healthy and high-quality foods, such as fruits and vegetables, have worse diet quality that children in households that are food secure. Additionally, evidence from adult studies link household FI to MASLD and liver fibrosis, and prior research of the PI has shown that exposure to household FI in early childhood was associated with a nearly 4 times increased odds of pediatric MASLD in middle childhood. Possible mechanisms linking household FI to pediatric MASLD include lower intake of fruits and vegetables, higher intake of caloric dense nutrient poor foods (e.g., sugar sweetened beverages), and less diversity of foods. Given consensus recommendations for the management of MASLD focus on lifestyle modification, i.e., diet and exercise to achieve weight loss, this proposal seeks to explore the association of household FI and pediatric MASLD disease severity and whether those effects are mediated by dietary intake. Study participants include children/adolescents with MASLD who are receiving care at UCSF's liver clinic and Weight Management for Teen and Child Health (WATCH) Clinic, a pediatric subspecialty clinic.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07090083
- Europe PMC full search
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Related trials
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Currently open trials in the same condition.
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- NCT06905795 — Screening and Intervention of MASLD in Children · NA · active not recruiting
Other University of California, San Francisco trials
Trials by the same sponsor.
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- NCT07534098 — Intervention for Hearing Health Among Native Americans · NA · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07090083 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of California, San Francisco
- Last refreshed: 2 September 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07090083.
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