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NCT07084207: REGEN
A Study to Expand the Use of Symani® Surgical System for Peripheral Nerve Repair
NA trial testing Symani® Surgical System in Nerve Injury in 100 participants. Currently enrolling.
18 December 2026
Quick facts
| Lead sponsor | MMI (Medical Microinstruments, Inc.) |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 100 |
| Start date | 18 December 2025 |
| Primary completion | 18 December 2026 |
| Estimated completion | 18 December 2027 |
| Sites | 1 location across Germany |
Drugs / interventions tested
- Symani® Surgical System
- Manual Surgery
Conditions studied
- Nerve Injury — all drugs for Nerve Injury →
- Peripheral Nerve Injuries — all drugs for Peripheral Nerve Injuries →
Sponsor
MMI (Medical Microinstruments, Inc.) — full company profile →
Who can join
Adults 18 to 70, any sex, with Nerve Injury or Peripheral Nerve Injuries. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The objective of this study is to evaluate the Symani System's safety and effectiveness for microsurgical nerve coaptation, following nerve injuries to the hand. This study will include participants with traumatic sensory nerve lesions of a finger nerve distal to the carpal tunnel who are treated with nerve suturing. The primary effectiveness endpoint is the two-point discrimination (2PD) test, at 6-months post index procedure. The primary safety endpoint is the intraoperative serious adverse event rate.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07084207
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Nerve Injury
Currently open trials in the same condition.
- NCT05365282 — Association Between Radial Artery Intervention and Development of Neuropathy in the Hand - A Prospective Study · recruiting
- NCT05593237 — Transcranial Magnetic Stimulation for Chronic Neuropathic Pain · NA · active not recruiting
- NCT04144972 — Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain · NA · recruiting
Other MMI (Medical Microinstruments, Inc.) trials
Trials by the same sponsor.
- NCT07311876 — Clinical Lymphedema Evaluation - Advancing Reconstruction of Head and Neck Lymphatics With Symani · NA · not yet recruiting
- NCT07178210 — Robotic-Enabled Microsurgical Intervention for Neurodegenerative Disease · NA · recruiting
- NCT06866197 — CONNECT: A Multi-Cohort, Prospective Investigation of the Symani® Surgical System · NA · recruiting
- NCT06725030 — A Post-market, Real-world Experience: Expanding Access to Care by Incorporating the Symani® Surgical System and Enabling · recruiting
- NCT06628219 — A Global, Prospective, Real-World, Investigation of the Symani® Surgical System for Microsurgical Anastomosis · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07084207 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by MMI (Medical Microinstruments, Inc.)
- Last refreshed: 3 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07084207.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing