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NCT07074561
The Synergism and Attenuation Effects of Electroacupuncture in the Treatment of Trigeminal Neuralgia
NA trial testing CBZ placebo in Trigeminal Neuralgia in 28 participants. Not yet recruiting.
31 December 2025
Quick facts
| Lead sponsor | Yuanyuan Wu |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 28 |
| Start date | 20 July 2025 |
| Primary completion | 31 December 2025 |
| Estimated completion | 31 December 2025 |
Drugs / interventions tested
- CBZ placebo
- CBZ — full drug profile →
- Electroacupuncture
- Sham electroacupuncture
Conditions studied
- Trigeminal Neuralgia — all drugs for Trigeminal Neuralgia →
Sponsor
Yuanyuan Wu — full company profile →
Who can join
Adults 18 to 75, any sex, with Trigeminal Neuralgia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Trigeminal neuralgia (TN), characterized by its refractory nature and recurrence, frequently leads to anxiety, depression, and insomnia, thereby significantly diminishing patients' quality of life and potentially inducing self-harm. Carbamazepine (CBZ) is the first-line medication for TN, yet it presents adverse effects such as addiction and the absence of analgesic effects upon cessation. Acupuncture, particularly electroacupuncture（EA）, has demonstrated efficacy in TN treatment, although its therapeutic outcomes are influenced by various factors. This multicenter, randomized controlled trial aims to evaluate the synergistic efficacy-enhancing and toxicity-reducing effects of the optimized protocol when combined with carbamazepine (CBZ) in treating trigeminal neuralgia (TN), thereby proposing novel therapeutic refinements for electroacupuncture treatment regimens in TN management.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07074561
- Europe PMC full search
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Related trials
Other trials of CBZ
Trials testing the same drug.
- NCT06893081 — A Study of Carbamazepine (CBZ) and MK-8527 in Healthy Adult Participants (MK-8527-012) · Phase 1 · completed
Other recruiting trials for Trigeminal Neuralgia
Currently open trials in the same condition.
- NCT07252453 — Comparison b/w Carbamazepine vs Oxcarbazepine in Treatment of Trigeminal Neuralgia · NA · active not recruiting
- NCT06684275 — Comparison of Pulsed and Thermal Radiofrequency for Trigeminal Neuralgia · NA · recruiting
- NCT06620172 — CT-guided vs Fluoroscopy-guided Trigeminal Ganglion Radiofrequency Thermocoagulation for Idiopathic Trigeminal Neuralgia · NA · recruiting
- NCT06849219 — Comparison of Oxcarbazepine Versus Carbamazepine in the Management of Trigeminal Neuralgia · Phase 4 · active not recruiting
- NCT06216886 — OnabotulinumtoxinA for Trigeminal Neuralgia · Phase 4 · recruiting
Other Yuanyuan Wu trials
Trials by the same sponsor.
- NCT06977932 — The Alternative Effects of Electroacupuncture in the Treatment of Trigeminal Neuralgia · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07074561 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Yuanyuan Wu
- Last refreshed: 20 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07074561.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing