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NCT06977932
The Alternative Effects of Electroacupuncture in the Treatment of Trigeminal Neuralgia
NA trial testing Carbarmazepine in Trigeminal Neuralgia in 126 participants. Not yet recruiting.
31 December 2028
Quick facts
| Lead sponsor | Yuanyuan Wu |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 126 |
| Start date | 1 March 2026 |
| Primary completion | 31 December 2028 |
| Estimated completion | 31 December 2028 |
Drugs / interventions tested
- Carbarmazepine — full drug profile →
- Sham Electroacupuncture
- Carbarmazepine Placebo
- Electroacupuncture
Conditions studied
- Trigeminal Neuralgia — all drugs for Trigeminal Neuralgia →
Sponsor
Yuanyuan Wu — full company profile →
Who can join
Adults 18 to 80, any sex, with Trigeminal Neuralgia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Trigeminal neuralgia (TN), characterized by its refractory nature and recurrence, frequently leads to anxiety, depression, and insomnia, thereby significantly diminishing patients' quality of life and potentially inducing self-harm. Carbamazepine (CBZ) is the first-line medication for TN, yet it presents adverse effects such as addiction and the absence of analgesic effects upon cessation. Acupuncture, particularly electroacupuncture(EA), has demonstrated efficacy in TN treatment, although its therapeutic outcomes are influenced by various factors. Consequently, this study aims to evaluate the clinical efficacy of EA for TN and its potential as an alternative to CBZ treatment.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Effect of Electroacupuncture for Trigeminal Neuralgia: Study Protocol for a Multicenter Randomized Controlled Trial.
Chen N, Xu M, Wang J, Wang D, et al · · 2026 · PMID 42261299 · DOI 10.2147/jpr.s616735 -
Effect of Electroacupuncture for Trigeminal Neuralgia: Study Protocol for a Multicenter Randomized Controlled Trial
Chen N, Xu M, Wang J, Wang D, et al · · 2026
Verify or expand the search:
- PubMed search for NCT06977932
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Trigeminal Neuralgia
Currently open trials in the same condition.
- NCT07252453 — Comparison b/w Carbamazepine vs Oxcarbazepine in Treatment of Trigeminal Neuralgia · NA · active not recruiting
- NCT06684275 — Comparison of Pulsed and Thermal Radiofrequency for Trigeminal Neuralgia · NA · recruiting
- NCT06620172 — CT-guided vs Fluoroscopy-guided Trigeminal Ganglion Radiofrequency Thermocoagulation for Idiopathic Trigeminal Neuralgia · NA · recruiting
- NCT06849219 — Comparison of Oxcarbazepine Versus Carbamazepine in the Management of Trigeminal Neuralgia · Phase 4 · active not recruiting
- NCT06216886 — OnabotulinumtoxinA for Trigeminal Neuralgia · Phase 4 · recruiting
Other Yuanyuan Wu trials
Trials by the same sponsor.
- NCT07074561 — The Synergism and Attenuation Effects of Electroacupuncture in the Treatment of Trigeminal Neuralgia · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06977932 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Yuanyuan Wu
- Last refreshed: 5 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06977932.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing