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NCT07034326
Electroacupuncture Combined With Immune Checkpoint Inhibitors as Adjuvant Therapy After Surgery for Early-stage Non-small Cell Lung Cancer
Phase 2, PHASE3 trial testing Electroacupuncture combined with immunotherapy in Non-Small Cell Lung Cancer in 405 participants. Currently enrolling.
31 December 2028
Quick facts
| Lead sponsor | Kong Fanming |
|---|---|
| Phase | Phase 2, PHASE3 |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 405 |
| Start date | 1 January 2025 |
| Primary completion | 31 December 2028 |
| Estimated completion | 31 December 2028 |
| Sites | 1 location across China |
Drugs / interventions tested
- Electroacupuncture combined with immunotherapy
- Zilongjin tablet combined with immunotherapy — full drug profile →
- Immunotherapy — full drug profile →
Conditions studied
- Non-Small Cell Lung Cancer — all drugs for Non-Small Cell Lung Cancer →
- Electroacupuncture — all drugs for Electroacupuncture →
- Immune Checkpoint Inhibitors — all drugs for Immune Checkpoint Inhibitors →
Sponsor
Kong Fanming — full company profile →
Who can join
Adults 18 to 80, any sex, with Non-Small Cell Lung Cancer or Electroacupuncture. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Postoperative immunoadjuvant therapy has been proven to significantly reduce the risk of recurrence after resectable NSCLC, and has become a new standard of postoperative adjuvant therapy for stage II-III NSCLC. Immunotherapy faces challenges such as immune resistance, heterogeneity of biomarker expression, and limitation of immune-suitable population. How to reduce the rate of recurrence and metastasis after surgery, enhance the therapeutic effect of immunotherapy, and then prolong the survival period and improve the quality of life, has become an urgent problem facing the current clinical. Based on the standards of evidence-based medicine, this study for the first time carried out a large sample, multi-center, randomized parallel controlled clinical study to obtain high-quality clinical evidence of the effectiveness and safety of electro-acupuncture and Zilongjin tablet synergic treatment, and formed a standard treatment plan of traditional Chinese medicine.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Harmonizing yin and yang, remodeling the microenvironment: the adjuvant potential of Chinese herbal medicine in tumor immunotherapy.
Gao X, Han Y, Yang L, Fang H, et al · · 2026 · PMID 41959898 · DOI 10.3389/fonc.2026.1806602 -
Research progress on traditional Chinese medicine-assisted immune checkpoint inhibitors therapy for solid tumors.
Liu Z, Xie Y, He Y, Chen K, et al · · 2026 · PMID 41694353 · DOI 10.3389/fimmu.2026.1723860
Verify or expand the search:
- PubMed search for NCT07034326
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Non-Small Cell Lung Cancer
Currently open trials in the same condition.
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- NCT07487883 — Cadherin 3(CDH3)-Targeted PET in Lung Malignant Tumors · recruiting
- NCT07413757 — CHOICE:Decision Factor of EGFR-TKI in Chinese IV NSCLC · recruiting
- NCT07460999 — Singing Training vs Usual Care 6-18 Months After Surgical Resection for Non-small Cell Lung Cancer (NSCLC) · NA · recruiting
- NCT07479277 — Progel Platinum for Air Leak Reduction After VATS Lobectomy for NSCLC · NA · recruiting
Other Kong Fanming trials
Trials by the same sponsor.
- NCT07239661 — Electroacupuncture Combined With PD-1 Inhibitor for ECOG2 Advanced NSCLC · NA · recruiting
- NCT07086300 — Electroacupuncture Combined With PD-1 Inhibitor for Elderly Patients With Advanced NSCLC · NA · recruiting
- NCT06548711 — Effect of Transcutaneous Acupoint Electrical Stimulation (TAES) on Postoperative Cough in Lung Cancer · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07034326 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Kong Fanming
- Last refreshed: 24 June 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07034326.
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