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DK222 Study at Hopkins
This Phase 1 clinical trial will test a new drug called \[18F\]DK222 in people with cancer. The goal is to see if the drug is safe, how it spreads through the body, how long it stays in the body, and how much radiation it gives off. \[18F\]DK222 is designed to attach strongly and specifically to a protein called PD-L1, which helps cancer hide from the immune system. This is a first in human study to collect preliminary safety and toxicity data of \[18F\]DK222.
Details
| Lead sponsor | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins |
|---|---|
| Phase | PHASE1 |
| Status | RECRUITING |
| Enrolment | 6 |
| Start date | Fri May 01 2026 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Sat May 01 2027 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Non-Small Cell Lung Cancer
- Urothelial Cancer
Interventions
- [18F]DK222 radiotracer
Countries
United States