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NCT07021300: EILC
Early Versus Interval Laparoscopic Cholecystectomy for Acute Cholecystitis
NA trial testing Early Laparoscopic Cholecystectomy in Acute Cholecystitis in 166 participants. Completed in 31 December 2024.
31 December 2024
Quick facts
| Lead sponsor | Lady Reading Hospital, Pakistan |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 166 |
| Start date | 1 May 2024 |
| Primary completion | 31 December 2024 |
| Estimated completion | 31 December 2024 |
| Sites | 1 location across Pakistan |
Drugs / interventions tested
- Early Laparoscopic Cholecystectomy
- Interval Laparoscopic Cholecystectomy
Conditions studied
- Acute Cholecystitis — all drugs for Acute Cholecystitis →
- Cholelithiasis — all drugs for Cholelithiasis →
- Gallbladder Diseases — all drugs for Gallbladder Diseases →
Sponsor
Lady Reading Hospital, Pakistan
Who can join
Adults 20 to 60, any sex, with Acute Cholecystitis or Cholelithiasis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study compares two different timing approaches for gallbladder removal surgery in patients with acute gallbladder inflammation (acute cholecystitis). When someone develops acute cholecystitis, doctors need to remove the gallbladder using a minimally invasive technique called laparoscopic surgery. However, there is ongoing debate about the best timing for this surgery. Some doctors prefer to operate early (within 3 days of diagnosis), while others prefer to wait and operate later (after 4 weeks of medical treatment). In this study, we randomly assigned 166 patients with acute cholecystitis to receive either: * Early surgery: Laparoscopic gallbladder removal within 72 hours of diagnosis * Delayed surgery: Laparoscopic gallbladder removal after 4 weeks of antibiotic treatment All surgeries were performed by the same experienced surgeon using standard techniques. We measured how long each surgery took, how many days patients stayed in the hospital, and how often the surgeon needed to switch from the minimally invasive approach to open surgery. The study found that patients who had early surgery had shorter operation times, went home from the hospital sooner, and were less likely to need open surgery compared to patients who waited 4 weeks for their operation. This research helps doctors and patients make better decisions about the timing of gallbladder surgery when someone has acute cholecystitis.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07021300
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Early Laparoscopic Cholecystectomy
Trials testing the same drug.
- NCT04511910 — How to Predict Postoperative Complications After Early Laparoscopic Cholecystectomy for Acute Cholecystitis: the Chole-R · completed
Other recruiting trials for Acute Cholecystitis
Currently open trials in the same condition.
- NCT07161960 — Early Versus Delayed Cholecystectomy After Percutaneous Cholecystostomy in Moderate and Severe Cholecystitis (ESCAPE) · NA · recruiting
- NCT06967597 — Conservative Versus Proactive Management of Acute Cholecystitis After EUS-guided Transmural Gallbladder Drainage: FUGITI · NA · recruiting
- NCT07006298 — One-year Outcomes by Index Treatment in Elderly Patients With Acute Cholecystitis · recruiting
- NCT06287112 — Prevention of Acute Cholecystitis With ETGBD · NA · recruiting
- NCT05732480 — Influence of Gut Microbiome in Gallstone Disease · recruiting
Other Lady Reading Hospital, Pakistan trials
Trials by the same sponsor.
- NCT07280975 — Comparing Polyglactin vs Polypropylene Sutures for Rectus Sheath Closure · NA · not yet recruiting
- NCT07501390 — Effectiveness Of Early Bed Mobility Exercises And Ambulation In Post Operative Cesarean Section Pain Reduction · NA · completed
- NCT07183930 — Tubeless vs Tube PCNL in Pediatric Nephrolithiasis: A Randomized Controlled Trial. · NA · completed
- NCT06021990 — Clopidogrel for the Prevention of Exacerbations in Severe COPD · Phase 3 · unknown
- NCT05255848 — Nebulised Heparin in Patients With COVID-19 Pneumonia · Phase 2, PHASE3 · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07021300 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Lady Reading Hospital, Pakistan
- Last refreshed: 13 June 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07021300.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing